topicMulberry Blood Glucose Randomized Trial
claimAfter 12 weeks of treatment, both SZ-A and canagliflozin significantly reduced HbA1c, fasting and postprandial glucose, 24 h mean blood glucose, and time above range (TAR).
evidence level2
citationLi H (2026)
sourceEffects of mulberry twig alkaloids and canagliflozin in inadequately controlled type 2 diabetes: a randomized controlled study based on flash glucose monitoring.
topicMulberry Blood Glucose Randomized Trial
claimIn contrast to canagliflozin, SZ-A significantly reduced postprandial glucose excursion (PPGE) after breakfast and dinner.
evidence level2
citationLi H (2026)
sourceEffects of mulberry twig alkaloids and canagliflozin in inadequately controlled type 2 diabetes: a randomized controlled study based on flash glucose monitoring.
topicMulberry Blood Glucose Randomized Trial
claimBoth SZ-A and canagliflozin also improved insulin resistance and enhanced insulin sensitivity in patients.
evidence level2
citationLi H (2026)
sourceEffects of mulberry twig alkaloids and canagliflozin in inadequately controlled type 2 diabetes: a randomized controlled study based on flash glucose monitoring.
topicMulberry Blood Glucose Randomized Trial
claimThis study compared the efficacy and safety of mulberry twig alkaloids (SZ-A) versus canagliflozin administration in poorly oral-antidiabetic controlled patients with type 2 diabetes mellitus (T2DM) by using the flash glucose monitoring (FGM) system.
evidence level2
citationLi H (2026)
sourceEffects of mulberry twig alkaloids and canagliflozin in inadequately controlled type 2 diabetes: a randomized controlled study based on flash glucose monitoring.
topicMulberry Blood Glucose Randomized Trial
claimAdditionally, the TCM symptom score was markedly reduced in the MTA group compared with the control group (P<0.05).
evidence level4
citationZhou Y (2026)
sourceMulberry Twig Alkaloids Combined With Insulin Infusion: Effects on Blood Glucose Variability in Type 2 Diabetes.
topicMulberry Blood Glucose Randomized Trial
claimBACKGROUND Glycemic variability is increasingly recognized as an important contributor to the development of diabetes-related complications in patients with type 2 diabetes mellitus (T2DM).
evidence level4
citationZhou Y (2026)
sourceMulberry Twig Alkaloids Combined With Insulin Infusion: Effects on Blood Glucose Variability in Type 2 Diabetes.
topicMulberry Blood Glucose Randomized Trial
claimContinuous subcutaneous insulin infusion (CSII) is effective in improving glycemic control; however, fluctuations in blood glucose can persist.
evidence level4
citationZhou Y (2026)
sourceMulberry Twig Alkaloids Combined With Insulin Infusion: Effects on Blood Glucose Variability in Type 2 Diabetes.