evidence table
Milk Thistle Liver Enzyme Randomized Trial Evidence Table
Structured evidence table for Milk Thistle Liver Enzyme Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Milk Thistle Liver Enzyme Randomized Trial | Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) lacks treatment options, with few evidence-based choices beyond lifestyle modification. | 2 | Messier H (2026) | Effectiveness and safety of an ayurvedic nutraceutical for improving clinical parameters of liver function in participants with metabolic dysfunction-associated steatotic liver disease: a randomized, placebo-controlled, preliminary phase 2 exploratory clinical trial. |
| Milk Thistle Liver Enzyme Randomized Trial | Discussion This study provides preliminary evidence that this organic nutraceutical may improve steatosis grade in individuals with MASLD. | 2 | Messier H (2026) | Effectiveness and safety of an ayurvedic nutraceutical for improving clinical parameters of liver function in participants with metabolic dysfunction-associated steatotic liver disease: a randomized, placebo-controlled, preliminary phase 2 exploratory clinical trial. |
| Milk Thistle Liver Enzyme Randomized Trial | This is the first clinical study to assess the efficacy of an organic liquid oral nutraceutical composed of turmeric extract, dandelion powder, milk thistle extract, and ginger powder in MASLD. | 2 | Messier H (2026) | Effectiveness and safety of an ayurvedic nutraceutical for improving clinical parameters of liver function in participants with metabolic dysfunction-associated steatotic liver disease: a randomized, placebo-controlled, preliminary phase 2 exploratory clinical trial. |
| Milk Thistle Liver Enzyme Randomized Trial | Chronic liver disease is emerging as a public health priority in India, with the incidence of metabolic dysfunction-associated steatotic liver disease ranging between 8 and 20% depending on the region and contributing to 10 to 15% of deaths due to chronic liver disease (). | 2 | Patel Ghanashyam (2026) | Long-term safety and efficacy of a highly purified plant-based nutraceutical for improving clinical parameters of liver function in healthy participants: a randomized, double-blind, placebo-controlled clinical trial |
| Milk Thistle Liver Enzyme Randomized Trial | Ginger () has been found to support healthy liver function, and to have antioxidant properties (). | 2 | Patel Ghanashyam (2026) | Long-term safety and efficacy of a highly purified plant-based nutraceutical for improving clinical parameters of liver function in healthy participants: a randomized, double-blind, placebo-controlled clinical trial |
| Milk Thistle Liver Enzyme Randomized Trial | Conventionally grown herbal supplements often contain pesticide residues (), which may be a health risk for consumers, given that chronic pesticide exposure and consumption may elevate the risk of a variety of negative health outcomes (). | 2 | Patel Ghanashyam (2026) | Long-term safety and efficacy of a highly purified plant-based nutraceutical for improving clinical parameters of liver function in healthy participants: a randomized, double-blind, placebo-controlled clinical trial |
| Milk Thistle Liver Enzyme Randomized Trial | 1 The liver has many functions that are important to human health, including detoxifying the blood, processing nutrients from food, regulating blood sugar levels and bile production, storing important vitamins, producing proteins involved in blood clotting, helping to maintain a healthy balance of cholesterol in the blood, and producing immune cells (). | 2 | Patel Ghanashyam (2026) | Long-term safety and efficacy of a highly purified plant-based nutraceutical for improving clinical parameters of liver function in healthy participants: a randomized, double-blind, placebo-controlled clinical trial |
Source documents
- Effectiveness and safety of an ayurvedic nutraceutical for improving clinical parameters of liver function in participants with metabolic dysfunction-associated steatotic liver disease: a randomized, placebo-controlled, preliminary phase 2 exploratory clinical trial.
- Long-term safety and efficacy of a highly purified plant-based nutraceutical for improving clinical parameters of liver function in healthy participants: a randomized, double-blind, placebo-controlled clinical trial