Structured evidence table for Milk Thistle Cognition Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Milk Thistle Cognition Randomized Trial | Importantly, once a stroke has occurred, the risk of recurrence and subsequent cognitive impairment increases significantly (). | 3 | Bu Fan (2026) | From diet to brain repair: natural bioactive compounds in post-ischemic stroke recovery |
| Milk Thistle Cognition Randomized Trial | Research on stroke pathophysiology has demonstrated that lifestyle modifications, including a healthy diet, regular physical activity, smoking cessation, and moderated alcohol intake, play crucial roles to reduce the risk of stroke (,). | 3 | Bu Fan (2026) | From diet to brain repair: natural bioactive compounds in post-ischemic stroke recovery |
| Milk Thistle Cognition Randomized Trial | We synthesize current evidence on the role of food-derived and natural bioactive compounds in post-ischemic stroke recovery. | 3 | Bu Fan (2026) | From diet to brain repair: natural bioactive compounds in post-ischemic stroke recovery |
| Milk Thistle Cognition Randomized Trial | 1 2 3 4 5 6 7–9 Ischemic stroke is the second leading cause of death and long-term disability worldwide, with global incidence numbers increasing ~4.07 million in 1990 to ~7.8 million in 2020 (). | 3 | Bu Fan (2026) | From diet to brain repair: natural bioactive compounds in post-ischemic stroke recovery |
| Milk Thistle Cognition Randomized Trial | Recent multi-cohort integrative analyses and meta-analyses have identified a PD-associated microbial profile enriched in pro-inflammatory species. | 3 | Chiang Han-Lin (2025) | Management of Gastrointestinal Symptoms in Parkinson’s Disease |
| Milk Thistle Cognition Randomized Trial | These dysbiotic changes are linked to compromised intestinal barrier integrity (“leaky gut”), systemic inflammation, and altered microbial metabolic functions and gene expression profiles.Growing evidence supports the involvement of the GI tract and the ENS in the pathophysiology of PD. | 3 | Chiang Han-Lin (2025) | Management of Gastrointestinal Symptoms in Parkinson’s Disease |
| Milk Thistle Cognition Randomized Trial | Increased intestinal permeability (“leaky gut”) might also facilitate systemic inflammation and impact the ENS and CNS. | 3 | Chiang Han-Lin (2025) | Management of Gastrointestinal Symptoms in Parkinson’s Disease |
| Milk Thistle Cognition Randomized Trial | Recently, increasing attention has been garnered to GI symptoms manifesting not only after a PD diagnosis, but in fact, occurring before the occurrence of motor dysfunction. | 3 | Chiang Han-Lin (2025) | Management of Gastrointestinal Symptoms in Parkinson’s Disease |
Source documents