Melissa Anxiety Randomized Trial Evidence Table

Structured evidence table for Melissa Anxiety Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Melissa Anxiety Randomized TrialThe VOLTAIRE trial aims to assess the impact of providing personalized cardiovascular risk information derived from computed tomography coronary angiography (CTCA) and a polygenic risk score (PRS) on cardiovascular risk factor modification.4Chen R (2026)Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
Melissa Anxiety Randomized TrialObjectives VOLTAIRE evaluates whether integrating CTCA and PRS into risk counseling enhances adherence to lifestyle and pharmacological interventions, ultimately improving cardiovascular outcomes among patients with T2D.4Chen R (2026)Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
Melissa Anxiety Randomized TrialParticipants are randomized 1:1:1 to receive: (1) risk factor counseling plus CTCA result, (2) risk factor counseling plus PRS result, or (3) standard risk factor counseling (control).4Chen R (2026)Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
Melissa Anxiety Randomized TrialBackground The contemporary management of type 2 diabetes (T2D) involves a multifaceted model of care integrating intensive management of lipids, blood pressure, and glucose, along with lifestyle modifications.4Chen R (2026)Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
Melissa Anxiety Randomized TrialHistorical use of medicinal plants was a result of cumulative trial and error experience and the transmission of traditional knowledge between generations, which later inspired systematic efforts to turn empirical claims into evidence-based arguments [].4Cîmpeanu Ioan-Alexandru (2026)Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
Melissa Anxiety Randomized TrialAlso, standardization and phytochemical reporting is the preferred method for interpreting the evidence base across Lamiaceae, as its composition is influenced by genetics, geography, cultivation, and post-harvest handling [,].4Cîmpeanu Ioan-Alexandru (2026)Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
Melissa Anxiety Randomized TrialAccordingly, the present review mapsfrom botanical and phytochemical fundamentals through recent preclinical advances and available clinical evidence, with emphasis on endpoints that best support translation and reproducibility across study types.4Cîmpeanu Ioan-Alexandru (2026)Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
Melissa Anxiety Randomized Trial1 2 2 1 3 4 1 2 4 5 Traditional healing systems and contemporary natural products research still depend on medicinal and aromatic plants, which continue to provide structurally diverse bioactive compounds with broad therapeutic potential [,].4Cîmpeanu Ioan-Alexandru (2026)Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
topicMelissa Anxiety Randomized Trial
claimThe VOLTAIRE trial aims to assess the impact of providing personalized cardiovascular risk information derived from computed tomography coronary angiography (CTCA) and a polygenic risk score (PRS) on cardiovascular risk factor modification.
evidence level4
citationChen R (2026)
sourceEvaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
topicMelissa Anxiety Randomized Trial
claimObjectives VOLTAIRE evaluates whether integrating CTCA and PRS into risk counseling enhances adherence to lifestyle and pharmacological interventions, ultimately improving cardiovascular outcomes among patients with T2D.
evidence level4
citationChen R (2026)
sourceEvaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
topicMelissa Anxiety Randomized Trial
claimParticipants are randomized 1:1:1 to receive: (1) risk factor counseling plus CTCA result, (2) risk factor counseling plus PRS result, or (3) standard risk factor counseling (control).
evidence level4
citationChen R (2026)
sourceEvaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
topicMelissa Anxiety Randomized Trial
claimBackground The contemporary management of type 2 diabetes (T2D) involves a multifaceted model of care integrating intensive management of lipids, blood pressure, and glucose, along with lifestyle modifications.
evidence level4
citationChen R (2026)
sourceEvaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
topicMelissa Anxiety Randomized Trial
claimHistorical use of medicinal plants was a result of cumulative trial and error experience and the transmission of traditional knowledge between generations, which later inspired systematic efforts to turn empirical claims into evidence-based arguments [].
evidence level4
citationCîmpeanu Ioan-Alexandru (2026)
sourceMelissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
topicMelissa Anxiety Randomized Trial
claimAlso, standardization and phytochemical reporting is the preferred method for interpreting the evidence base across Lamiaceae, as its composition is influenced by genetics, geography, cultivation, and post-harvest handling [,].
evidence level4
citationCîmpeanu Ioan-Alexandru (2026)
sourceMelissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
topicMelissa Anxiety Randomized Trial
claimAccordingly, the present review mapsfrom botanical and phytochemical fundamentals through recent preclinical advances and available clinical evidence, with emphasis on endpoints that best support translation and reproducibility across study types.
evidence level4
citationCîmpeanu Ioan-Alexandru (2026)
sourceMelissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies
topicMelissa Anxiety Randomized Trial
claim1 2 2 1 3 4 1 2 4 5 Traditional healing systems and contemporary natural products research still depend on medicinal and aromatic plants, which continue to provide structurally diverse bioactive compounds with broad therapeutic potential [,].
evidence level4
citationCîmpeanu Ioan-Alexandru (2026)
sourceMelissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies

Source documents

  1. Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients With Diabetes: Rationale and Design of the VOLTAIRE Study.
  2. Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies