topicMct Oil Cognition Randomized Trial
claimEK supplementation was associated with a statistically significant improvement in cognitive performance compared with placebo (SMD = 0.29, 95% CI 0.16-0.41; p p = 0.083), study duration (acute vs.
evidence level1
citationBonnechère B (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.
topicMct Oil Cognition Randomized Trial
claimDiscussion EK supplementation is associated with modest improvements in cognitive performance across diverse populations and study designs.
evidence level1
citationBonnechère B (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.
topicMct Oil Cognition Randomized Trial
claimIntroduction Cognitive function is closely linked to brain energy metabolism and may be compromised by aging, metabolic stress, and neuropsychiatric disease.
evidence level1
citationBonnechère B (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.
topicMct Oil Cognition Randomized Trial
claimKetone bodies can serve as an alternative cerebral fuel and may also exert signaling effects relevant to cognition.
evidence level1
citationBonnechère B (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.
topicMct Oil Cognition Randomized Trial
claimBackground and objectives Postprandial hyperglycemia is a modifiable determinant of type 2 diabetes risk and vascular complications.
evidence level4
citationKodama K (2026)
sourceEffect of Adding Medium-Chain Triglyceride (MCT) Oil to Rice on Postprandial Glucose Response in Healthy Adults: A Pragmatic Within-Subject Trial.
topicMct Oil Cognition Randomized Trial
claimCompared with the rice-only meal, the MCT meal significantly reduced interstitial glucose concentrations at 45, 60, and 75 minutes and lowered iAUC₀-₆₀, iAUC₀-₉₀, and iAUC₀-₁₂₀.
evidence level4
citationKodama K (2026)
sourceEffect of Adding Medium-Chain Triglyceride (MCT) Oil to Rice on Postprandial Glucose Response in Healthy Adults: A Pragmatic Within-Subject Trial.
topicMct Oil Cognition Randomized Trial
claimMedium-chain triglycerides (MCTs), absorbed via the portal vein, are rapidly oxidized in the liver and can stimulate glucagon-like peptide-1 (GLP-1) secretion and increase ketone body production, mechanisms that may attenuate postprandial glycemia.
evidence level4
citationKodama K (2026)
sourceEffect of Adding Medium-Chain Triglyceride (MCT) Oil to Rice on Postprandial Glucose Response in Healthy Adults: A Pragmatic Within-Subject Trial.