topicMaca Stress Support Randomized Trial
claimAeromonas caviae is a pathogenic microorganism that causes a wide spectrum of diseases in fish and humans and is often associated with aquatic environments and isolated from foods and animals.
evidence level4
citationMoreira VH (2025)
source<i>Aeromonas caviae</i> subsp. <i>aquatica</i> subsp. nov., a New Multidrug-Resistant Subspecies Isolated from a Drinking Water Storage Tank.
topicMaca Stress Support Randomized Trial
claimThe increasing prevalence and dissemination of multidrug-resistant bacteria represent a serious concern for public health.
evidence level4
citationMoreira VH (2025)
source<i>Aeromonas caviae</i> subsp. <i>aquatica</i> subsp. nov., a New Multidrug-Resistant Subspecies Isolated from a Drinking Water Storage Tank.
topicMaca Stress Support Randomized Trial
claimA prospective cohort study of 428 couples in infertility clinics found that 29% of couples used a CAM modality for infertility treatment, with 17% specifically using herbal therapies over the course of 18 months ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicMaca Stress Support Randomized Trial
claimConcurrent use of herbal medicines with prescription medications is reported among 20%–30% of prescription drug users in the United States; there is evidence via in vitro and in vivo studies that herbal therapies can act as metabolic inhibitors or inducers of prescription medications when used in combination ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicMaca Stress Support Randomized Trial
claimRisks of herbal-drug interactions span from side effects (eg, bleeding, cardiotoxicity, hypoglycemia, hypotension) to altered pharmacokinetics (eg, decreased absorption, increased metabolism) of medications ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicMaca Stress Support Randomized Trial
claim1 1 2 3 4 The Center for Disease Control’s (CDC) 2017 National Health and Nutrition Examination Survey estimated that, on average, 57% of the United States population uses dietary supplements, with botanicals or “herbal supplements” comprising 5.1–8.3% of these supplements ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice