topicLycopene Skin Hydration Randomized Trial
claimAtopic dermatitis (AD) is a persistent, relapsing skin inflammatory disorder characterised by epidermal barrier dysfunction, immune system anomalies, and microbial dysbiosis.
evidence level3
citationVyas J (2026)
sourceAdvanced delivery of natural bioactive compounds for atopic dermatitis: a review of polymeric conjugates and nanocarriers.
topicLycopene Skin Hydration Randomized Trial
claimCurrent therapies encompass calcineurin inhibitors, topical corticosteroids, and synthetic drugs such as JAK inhibitors and biologics, which, despite their efficacy, have safety issues and constraints on prolonged use.
evidence level3
citationVyas J (2026)
sourceAdvanced delivery of natural bioactive compounds for atopic dermatitis: a review of polymeric conjugates and nanocarriers.
topicLycopene Skin Hydration Randomized Trial
claimThe aim of this narrative review is to evaluate the evidence for several of the most common supplements for hair, skin, and nails, as well as potential concerns.
evidence level3
citationShing Vivian (2025)
sourceBenefits and risks of hair, skin, and nail supplements in older adults
topicLycopene Skin Hydration Randomized Trial
claimMay result in copper deficiency.Excess zinc may also interfere with the efficacy of medications such as antibiotics DHEA Increases skin hydration and thickness Limited data to ascertain if the benefits outweigh the risks 7 25 to 50 mg/d in older participants Increase in testosterone may cause hirsutism and acne.
evidence level3
citationShing Vivian (2025)
sourceBenefits and risks of hair, skin, and nail supplements in older adults
topicLycopene Skin Hydration Randomized Trial
claim9 10 9 Biotin can be naturally found in foods such as egg yolk, liver, cereals, vegetables, and rice.Biotin is also created as a byproduct by bacteria in the gut microbiome.For adults, the Food and Nutrition Board of the Institute of Medicine recommends a dietary intake of 30 mcg/d.
evidence level3
citationShing Vivian (2025)
sourceBenefits and risks of hair, skin, and nail supplements in older adults
topicLycopene Skin Hydration Randomized Trial
claim1 2 Patients often seek advice for skin changes caused by years of sun exposure, nutrient deficiencies, genetics, and other factors.
evidence level3
citationShing Vivian (2025)
sourceBenefits and risks of hair, skin, and nail supplements in older adults