topicLycopene Skin Aging Randomized Trial
claimAt the cellular level, senescent cells exhibit reduced proliferative capacity and cell cycle arrest, accompanied by the production of senescence-associated secretory phenotype (SASP) [].
evidence level3
citationLan Meng (2026)
sourceGut microbiota and aging: current understanding and future perspectives
topicLycopene Skin Aging Randomized Trial
claimGut microbiota dysbiosis is closely associated with multiple organ functional decline, immunosenescence, increased chronic inflammation levels, and weakened gut barrier function in the elderly, all of which are "signs of aging" [,].
evidence level3
citationLan Meng (2026)
sourceGut microbiota and aging: current understanding and future perspectives
topicLycopene Skin Aging Randomized Trial
claimNumerous studies have shown that, compared to young people, the species richness and alpha diversity of gut microbiota in elderly people are generally reduced.
evidence level3
citationLan Meng (2026)
sourceGut microbiota and aging: current understanding and future perspectives
topicLycopene Skin Aging Randomized Trial
claim1 2 3 3 4 5 6 7 8 9 10 Aging is the progressive decline of the body's molecules, cells, and functions over time, eventually leading to dysfunction and death [,].
evidence level3
citationLan Meng (2026)
sourceGut microbiota and aging: current understanding and future perspectives
topicLycopene Skin Aging Randomized Trial
claim1 2 3 4 3 4 5 7 8 11 12 14 15 17 A diet rich in phytonutrients found in fruits and vegetables (FV) is critical for optimal health [,].
evidence level4
citationJilcott Pitts Stephanie B. (2025)
sourceDaily intake of a lycopene-rich juice is associated with reductions in inflammatory markers but not increases in skin carotenoids in a pilot study among participants with obesity
topicLycopene Skin Aging Randomized Trial
claimDiets rich in carotenoids are linked with positive health outcomes, including reductions in the risk of cardiovascular disease and certain cancers [,].
evidence level4
citationJilcott Pitts Stephanie B. (2025)
sourceDaily intake of a lycopene-rich juice is associated with reductions in inflammatory markers but not increases in skin carotenoids in a pilot study among participants with obesity
topicLycopene Skin Aging Randomized Trial
claimOne mechanism by which carotenoids may reduce cardiovascular disease and cancer risk is via reductions in lipid peroxidation and inflammation [,].
evidence level4
citationJilcott Pitts Stephanie B. (2025)
sourceDaily intake of a lycopene-rich juice is associated with reductions in inflammatory markers but not increases in skin carotenoids in a pilot study among participants with obesity