topicLuteolin Cognition Randomized Trial
claim1 5 6 These compounds are widely present in plants and are included in the human and animal diet [], being found mainly in the vacuoles of plant cells in the form of C-glycosides or O-glycosides, acting as attractants to pollinators and symbionts [e.g., sunscreens against ultraviolet (UV) radiation, allelochemicals, and antimicrobial and antiherbivore factors] [,].
evidence level3
citationPiva Maiara (2026)
sourceFlavonoids as Nutraceuticals to Treat Inflammatory Diseases: Focusing on Quercetin, Kaempferol, Luteolin, Apigenin, Epicatechin and Their Effects on Hepatic, Nervous, and Pulmonary Systems
topicLuteolin Cognition Randomized Trial
claim1 1 7 Among the classes, isoflavones (present in soybean), flavonols (present in teas, onions, red wine, olive oil, among others), and flavones (present in fruit skins, buckwheat, red pepper, among others) are the flavonoids found in the greatest quantity in foods consumed by humans [].
evidence level3
citationPiva Maiara (2026)
sourceFlavonoids as Nutraceuticals to Treat Inflammatory Diseases: Focusing on Quercetin, Kaempferol, Luteolin, Apigenin, Epicatechin and Their Effects on Hepatic, Nervous, and Pulmonary Systems
topicLuteolin Cognition Randomized Trial
claim2 8 9 10 11 The benefits of flavonoid-rich foods consumption are shown against diseases that reduce lifespan due to their protective role against oxidative damage, a condition associated with many non-communicable diseases such as cardiovascular diseases, diabetes, cancer, and dementia [,].
evidence level3
citationPiva Maiara (2026)
sourceFlavonoids as Nutraceuticals to Treat Inflammatory Diseases: Focusing on Quercetin, Kaempferol, Luteolin, Apigenin, Epicatechin and Their Effects on Hepatic, Nervous, and Pulmonary Systems
topicLuteolin Cognition Randomized Trial
claim1 Figure 1 2 Plant-based food sources and their derivatives are more than ever the aim of scientific research due to their medicinal and health-improving properties.
evidence level3
citationPiva Maiara (2026)
sourceFlavonoids as Nutraceuticals to Treat Inflammatory Diseases: Focusing on Quercetin, Kaempferol, Luteolin, Apigenin, Epicatechin and Their Effects on Hepatic, Nervous, and Pulmonary Systems
topicLuteolin Cognition Randomized Trial
claimFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicLuteolin Cognition Randomized Trial
claimThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicLuteolin Cognition Randomized Trial
claimIt should be noted that the present work consists of a review and not a dosing guideline.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicLuteolin Cognition Randomized Trial
claim1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience