Structured evidence table for Lactoferrin Supplementation Skin Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lactoferrin Supplementation Skin Health Randomized Trial | 11 12 11 13 14 15 16 17 18 19 Since the beginning of the COVID-19 crisis, public interest in hygiene, immunity, and inflammation has increased. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Supplementation Skin Health Randomized Trial | Dairy intake, particularly low-fat products, has been associated with reduced COVID-19 severity and hospitalization [,]. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Supplementation Skin Health Randomized Trial | More broadly, diets rich in fruits, vegetables, and omega-3s, and low in processed foods, may reduce inflammation and infection risk [,,], whereas malnutrition and obesity impair immunity and increase COVID-19 severity []. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Supplementation Skin Health Randomized Trial | 1 The innate immune system provides rapid, nonspecific defense through barriers, cytokines, and cells such as macrophages, dendritic cells, and NK cells, while the adaptive system generates antigen-specific and long-lasting protection via T and B lymphocytes, forming an integrated network essential for host defense []. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Supplementation Skin Health Randomized Trial | These peptides have been associated with immune regulation, anti-inflammatory, and antimicrobial properties [,], possibly modulating the gut microbiome [] and exhibiting systemic activity to mitigate microbial infections []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Supplementation Skin Health Randomized Trial | In a clinical study, lactoferrin supplementation has been linked to a pronounced increase in circulating neutrophil precursors, and an associated reduction in TNF-α and IL-6 production []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Supplementation Skin Health Randomized Trial | Although the mechanisms described here are associated with direct immune system regulation, lactoferrin also works through biochemical and cellular mechanisms that make it relevant for protection against environmental stressors such as pathogens and UV radiation [,], making it particularly relevant for hair and skin applications. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Supplementation Skin Health Randomized Trial | 1 1 2 3 4 1 4 Lactoferrin is a multifunctional, iron-binding glycoprotein that has protective and tissue healing capacities throughout the life of an organism []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
Source documents