Structured evidence table for Lactoferrin Skin Acne Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lactoferrin Skin Acne Randomized Trial | They secrete cytokines and chemokines, promoting the recruitment of macrophages and polymorphs to the skin injury site, and express Toll-like receptors (TLRs), recognizing pathogen-associated molecular patterns (PAMPs). | 3 | Guryanova Svetlana V. (2026) | Human and Marine Host Defense Peptides for Healthy Skin |
| Lactoferrin Skin Acne Randomized Trial | Dermcidin helps to limit bacterial colonization on the skin during the initial hours after sweating, and therefore effectively reduces the risk of infection by pathogens encountered in the environment. | 3 | Guryanova Svetlana V. (2026) | Human and Marine Host Defense Peptides for Healthy Skin |
| Lactoferrin Skin Acne Randomized Trial | Patients with atopic dermatitis (AD), for instance, have significantly reduced levels of dermcidin peptides in their sweat []. | 3 | Guryanova Svetlana V. (2026) | Human and Marine Host Defense Peptides for Healthy Skin |
| Lactoferrin Skin Acne Randomized Trial | 1 2 3 The skin provides the first line of body defense system, employing both physical and chemical barriers to repel pathogens. | 3 | Guryanova Svetlana V. (2026) | Human and Marine Host Defense Peptides for Healthy Skin |
| Lactoferrin Skin Acne Randomized Trial | These peptides have been associated with immune regulation, anti-inflammatory, and antimicrobial properties [,], possibly modulating the gut microbiome [] and exhibiting systemic activity to mitigate microbial infections []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Acne Randomized Trial | In a clinical study, lactoferrin supplementation has been linked to a pronounced increase in circulating neutrophil precursors, and an associated reduction in TNF-α and IL-6 production []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Acne Randomized Trial | Although the mechanisms described here are associated with direct immune system regulation, lactoferrin also works through biochemical and cellular mechanisms that make it relevant for protection against environmental stressors such as pathogens and UV radiation [,], making it particularly relevant for hair and skin applications. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Acne Randomized Trial | 1 1 2 3 4 1 4 Lactoferrin is a multifunctional, iron-binding glycoprotein that has protective and tissue healing capacities throughout the life of an organism []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
Source documents