topicLactoferrin Skin Acne Randomized Trial
claimThey secrete cytokines and chemokines, promoting the recruitment of macrophages and polymorphs to the skin injury site, and express Toll-like receptors (TLRs), recognizing pathogen-associated molecular patterns (PAMPs).
evidence level3
citationGuryanova Svetlana V. (2026)
sourceHuman and Marine Host Defense Peptides for Healthy Skin
topicLactoferrin Skin Acne Randomized Trial
claimDermcidin helps to limit bacterial colonization on the skin during the initial hours after sweating, and therefore effectively reduces the risk of infection by pathogens encountered in the environment.
evidence level3
citationGuryanova Svetlana V. (2026)
sourceHuman and Marine Host Defense Peptides for Healthy Skin
topicLactoferrin Skin Acne Randomized Trial
claimPatients with atopic dermatitis (AD), for instance, have significantly reduced levels of dermcidin peptides in their sweat [].
evidence level3
citationGuryanova Svetlana V. (2026)
sourceHuman and Marine Host Defense Peptides for Healthy Skin
topicLactoferrin Skin Acne Randomized Trial
claim1 2 3 The skin provides the first line of body defense system, employing both physical and chemical barriers to repel pathogens.
evidence level3
citationGuryanova Svetlana V. (2026)
sourceHuman and Marine Host Defense Peptides for Healthy Skin
topicLactoferrin Skin Acne Randomized Trial
claimWe link mechanistic insights with clinical and preclinical evidence and uniquely map molecular functions to dermatologic and trichologic outcomes.
evidence level4
citationKaplan N (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.
topicLactoferrin Skin Acne Randomized Trial
claimLactoferrin is a naturally occurring bioactive glycoprotein that is part of the body's innate immune system and has essential roles in iron metabolism, microbial defense, inflammation regulation, and tissue repair.
evidence level4
citationKaplan N (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.
topicLactoferrin Skin Acne Randomized Trial
claimIt supports the natural regulation of iron bioavailability in skin and hair follicles, helping to reduce excess free-iron-driven oxidative stress while preserving levels of necessary iron for cellular functions.
evidence level4
citationKaplan N (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.