evidence table

Lactoferrin Gut Health Meta-Analysis Evidence Table

Structured evidence table for Lactoferrin Gut Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Lactoferrin Gut Health Meta-AnalysisWhile advances in perinatal medicine and neonatal intensive care have significantly improved the survival rates of preterm infants, this progress has been accompanied by a rise in the incidence of NEC, with a global prevalence of approximately 7.0% among infants with extremely low birth weight (ELBW).3Chen Siyi (2026)Synergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
Lactoferrin Gut Health Meta-AnalysisThe precise etiology and pathogenesis of NEC remain incompletely understood; it is generally posited to be associated with multiple factors, such as intestinal barrier immaturity in preterm infants, gut microbiota dysbiosis, inappropriate feeding practices, and abnormal inflammatory responses (,).3Chen Siyi (2026)Synergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
Lactoferrin Gut Health Meta-AnalysisThese antimicrobial proteins, together with HMOs, support the establishment of a healthy microbiota, crucial for reducing the risk of NEC.3Chen Siyi (2026)Synergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
Lactoferrin Gut Health Meta-Analysis1 2 3 4 5 6 Necrotizing enterocolitis (NEC) is a critical intestinal emergency that predominantly affects neonates, especially those born prematurely.3Chen Siyi (2026)Synergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
Lactoferrin Gut Health Meta-AnalysisAs an integral component of the human diet, dairy products are rich in high-quality protein, lactoferrin, conjugated linoleic acid, calcium, vitamin D, and various other nutrients and bioactive compounds.4Wang M (2026)A narrative review of nutritional components, health effects, and disease prevention mechanisms of dairy products.
Lactoferrin Gut Health Meta-AnalysisThey exert broad health benefits through core mechanisms involving multiple pathways and targets.4Wang M (2026)A narrative review of nutritional components, health effects, and disease prevention mechanisms of dairy products.
topicLactoferrin Gut Health Meta-Analysis
claimWhile advances in perinatal medicine and neonatal intensive care have significantly improved the survival rates of preterm infants, this progress has been accompanied by a rise in the incidence of NEC, with a global prevalence of approximately 7.0% among infants with extremely low birth weight (ELBW).
evidence level3
citationChen Siyi (2026)
sourceSynergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
topicLactoferrin Gut Health Meta-Analysis
claimThe precise etiology and pathogenesis of NEC remain incompletely understood; it is generally posited to be associated with multiple factors, such as intestinal barrier immaturity in preterm infants, gut microbiota dysbiosis, inappropriate feeding practices, and abnormal inflammatory responses (,).
evidence level3
citationChen Siyi (2026)
sourceSynergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
topicLactoferrin Gut Health Meta-Analysis
claimThese antimicrobial proteins, together with HMOs, support the establishment of a healthy microbiota, crucial for reducing the risk of NEC.
evidence level3
citationChen Siyi (2026)
sourceSynergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
topicLactoferrin Gut Health Meta-Analysis
claim1 2 3 4 5 6 Necrotizing enterocolitis (NEC) is a critical intestinal emergency that predominantly affects neonates, especially those born prematurely.
evidence level3
citationChen Siyi (2026)
sourceSynergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
topicLactoferrin Gut Health Meta-Analysis
claimAs an integral component of the human diet, dairy products are rich in high-quality protein, lactoferrin, conjugated linoleic acid, calcium, vitamin D, and various other nutrients and bioactive compounds.
evidence level4
citationWang M (2026)
sourceA narrative review of nutritional components, health effects, and disease prevention mechanisms of dairy products.
topicLactoferrin Gut Health Meta-Analysis
claimThey exert broad health benefits through core mechanisms involving multiple pathways and targets.
evidence level4
citationWang M (2026)
sourceA narrative review of nutritional components, health effects, and disease prevention mechanisms of dairy products.

Source documents

  1. Synergistic regulation of gut microbiota and metabolites by breast milk and probiotics in the prevention of neonatal necrotizing enterocolitis: mechanisms and prospects
  2. A narrative review of nutritional components, health effects, and disease prevention mechanisms of dairy products.