topicL-Citrulline Endurance Exercise Meta-Analysis
claimRisk of bias, small-study effects, sensitivity analyses, and GRADE certainty were assessed.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimCM supplementation was associated with a small improvement in overall exercise performance (g = 0.16, p = 0.01); however, prediction intervals were wide and statistical power was limited.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimCurrent evidence appeared more stable for acute than chronic supplementation, although the protocol subgroup difference remained uncertain.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimBackground: Citrulline malate (CM) is commonly used as an ergogenic supplement, but its effects on exercise performance and perceived exertion remain uncertain.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimNext, we integrate evidence on the ergogenic effects of various dietary interventions with existing knowledge on the perception of effort.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimBeta-alanine, caffeine or carbohydrate mouth rinsing are examples of evidence-based ergogenic aids.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimConclusion While current evidence supports a key role for dietary interventions on endurance performance by influencing individuals' perceived effort, more research is needed to determine the optimal doses and precise formulations for different sports, in order to employ a personalized strategy.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicL-Citrulline Endurance Exercise Meta-Analysis
claimBackground Exercise tolerance is a pivotal factor in determining athletic competitive success, as well as mobility and quality of life in elderly individuals and those afflicted by chronic ailments.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.