evidence table

L-Carnitine Supplementation Cognitive Performance Randomized Trial Evidence Table

Name: L-Carnitine Supplementation Cognitive Performance Randomized Trial Evidence Table
Creator: Migaku
License: https://creativecommons.org/licenses/by/4.0/

Structured evidence table for L-Carnitine Supplementation Cognitive Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topic	claim	evidence level	citation	source
L-Carnitine Supplementation Cognitive Performance Randomized Trial	1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults ().	3	Wang Xiaolan (2026)	Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
L-Carnitine Supplementation Cognitive Performance Randomized Trial	1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence ().	3	Wang Xiaolan (2026)	Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
L-Carnitine Supplementation Cognitive Performance Randomized Trial	Low circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,).	3	Wang Xiaolan (2026)	Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
L-Carnitine Supplementation Cognitive Performance Randomized Trial	In this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials.	3	Wang Xiaolan (2026)	Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
L-Carnitine Supplementation Cognitive Performance Randomized Trial	This narrative review evaluates Meldonium's biochemical mechanisms, pharmacokinetics, safety profile, and the quality of evidence surrounding its use in athletes.	4	Malm C (2026)	Meldonium and human sport performance: a narrative review evaluating the evidence for ergogenic potential.
L-Carnitine Supplementation Cognitive Performance Randomized Trial	Existing human performance studies exhibit a high risk of bias and methodological flaws.	4	Malm C (2026)	Meldonium and human sport performance: a narrative review evaluating the evidence for ergogenic potential.
L-Carnitine Supplementation Cognitive Performance Randomized Trial	Meldonium has attracted considerable attention in sports due to its suggested effects on energy metabolism and high-profile doping cases.	4	Malm C (2026)	Meldonium and human sport performance: a narrative review evaluating the evidence for ergogenic potential.