L-Carnitine Exercise Recovery Randomized Trial Evidence Table

Structured evidence table for L-Carnitine Exercise Recovery Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
L-Carnitine Exercise Recovery Randomized TrialThe results of a prior study confirmed the protective benefits of L-carnitine due to suppression of inflammation, oxidative stress, and increased autophagy (Khedr and Werida).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
L-Carnitine Exercise Recovery Randomized TrialSeveral experimental and clinical studies have suggested that L-carnitine supplementation may confer cardiovascular benefits in CAD patients, including improved cardiac metabolism, reduced oxidative stress, attenuation of inflammatory responses, and enhanced functional outcomes (Da Silva Guimarães et al.; Dastan et al.; Lee et al.; Lee et al.; Pastoris et al.; Singhai et al.; Tarantini et al.; Xue et al.).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
L-Carnitine Exercise Recovery Randomized TrialTo our best knowledge, this is the first systematic review to address these gaps by synthesizing evidence in CAD patients across mechanistic markers such as oxidative stress, inflammatory mediators, autophagy-related markers and post-PCI myocardial-injury biomarkers together with clinical endpoints such as ventricular arrythmia, mortality and angina.1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
L-Carnitine Exercise Recovery Randomized Trial2019 2019 2015 Cardiovascular disease (CVD) is the predominant cause of death worldwide, with a substantial proportion attributable to ischemic heart disease, caused by atherosclerotic coronary artery disease (CAD) (Glovaci et al.; Sarrafzadegan and Mohammadifard).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
L-Carnitine Exercise Recovery Randomized TrialAging is closely associated with oxidative stress, mitochondrial dysfunction, chronic inflammation, and progressive declines in muscle and cognitive function.4Wang X (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults.
L-Carnitine Exercise Recovery Randomized TrialEvidence on NAC suggests context-dependent effects, with supplementation improving glutathione availability, fatigue resistance, and exercise performance in individuals with low baseline glutathione, while results remain inconsistent in healthy populations.4Wang X (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults.
L-Carnitine Exercise Recovery Randomized TrialExercise is widely recognized as the most effective non-pharmacological strategy to counteract these processes; however, its benefits may be potentiated by targeted nutritional interventions.4Wang X (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults.

Source documents

  1. Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
  2. Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults.