gut health

Konjac Glucomannan Gut Health Randomized Trial Evidence Table

Structured evidence table for Konjac Glucomannan Gut Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Konjac Glucomannan Gut Health Randomized Trial1 2 3 4 5 6 7 For modern high-risk diseases—including metabolic disorders, inflammatory bowel diseases, autoimmune conditions, and neurodegenerative disorders—current treatment strategies (e.g., insulin sensitizers and anti-inflammatory drugs) have shown some efficacy, but long-term effectiveness and safety remain major challenges [].3Yu Yufen (2025)Interaction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
Konjac Glucomannan Gut Health Randomized TrialDespite their heterogeneous clinical manifestations, growing evidence suggests that their pathogenesis is closely linked to gut microbiota dysbiosis.3Yu Yufen (2025)Interaction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
Konjac Glucomannan Gut Health Randomized TrialThus, dietary interventions targeting gut microbiota modulation hold promise as a novel therapeutic approach for mitigating modern high-risk diseases.3Yu Yufen (2025)Interaction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
Konjac Glucomannan Gut Health Randomized TrialLactate accumulation in some cases may be associated with the severity of inflammatory bowel disease and other health conditions (Vernia et al., Hove et al., Louis et al.).4Lo Galiana (2026)Metabolism of β -mannans by representative, understudied Bacillota species from the human colon
Konjac Glucomannan Gut Health Randomized Trialwere reported to be increased in individuals with active inflammatory bowel disease while butyrate-producing Bacillota were decreased (Wang et al.).4Lo Galiana (2026)Metabolism of β -mannans by representative, understudied Bacillota species from the human colon
Konjac Glucomannan Gut Health Randomized Trial2020 2018 1 2019a 1993 1967 1 More recently, other saccharides including mannans and their respective oligosaccharides (Saville and Saville) have also been considered to provide health benefits and β-mannans are mostly found in plants (Singh et al.); these glycans can be insoluble or water-soluble.4Lo Galiana (2026)Metabolism of β -mannans by representative, understudied Bacillota species from the human colon
Konjac Glucomannan Gut Health Randomized Trial2016 2009 2012 2013 2015 2003 2025 2009 2011 2017 2015 2017 2016 The human gastrointestinal tract hosts a dense and complex microbial ecosystem (Sender et al.), with most bacteria belonging to the Bacillota and Bacteroidetes phyla and lower numbers belonging to the Actinobacteria, Proteobacteria and Verrucomicrobia phyla (Tap et al., The Human Microbiome Project Consortium, Duncan and Flint).4Lo Galiana (2026)Metabolism of β -mannans by representative, understudied Bacillota species from the human colon
topicKonjac Glucomannan Gut Health Randomized Trial
claim1 2 3 4 5 6 7 For modern high-risk diseases—including metabolic disorders, inflammatory bowel diseases, autoimmune conditions, and neurodegenerative disorders—current treatment strategies (e.g., insulin sensitizers and anti-inflammatory drugs) have shown some efficacy, but long-term effectiveness and safety remain major challenges [].
evidence level3
citationYu Yufen (2025)
sourceInteraction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
topicKonjac Glucomannan Gut Health Randomized Trial
claimDespite their heterogeneous clinical manifestations, growing evidence suggests that their pathogenesis is closely linked to gut microbiota dysbiosis.
evidence level3
citationYu Yufen (2025)
sourceInteraction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
topicKonjac Glucomannan Gut Health Randomized Trial
claimThus, dietary interventions targeting gut microbiota modulation hold promise as a novel therapeutic approach for mitigating modern high-risk diseases.
evidence level3
citationYu Yufen (2025)
sourceInteraction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
topicKonjac Glucomannan Gut Health Randomized Trial
claimLactate accumulation in some cases may be associated with the severity of inflammatory bowel disease and other health conditions (Vernia et al., Hove et al., Louis et al.).
evidence level4
citationLo Galiana (2026)
sourceMetabolism of β -mannans by representative, understudied Bacillota species from the human colon
topicKonjac Glucomannan Gut Health Randomized Trial
claimwere reported to be increased in individuals with active inflammatory bowel disease while butyrate-producing Bacillota were decreased (Wang et al.).
evidence level4
citationLo Galiana (2026)
sourceMetabolism of β -mannans by representative, understudied Bacillota species from the human colon
topicKonjac Glucomannan Gut Health Randomized Trial
claim2020 2018 1 2019a 1993 1967 1 More recently, other saccharides including mannans and their respective oligosaccharides (Saville and Saville) have also been considered to provide health benefits and β-mannans are mostly found in plants (Singh et al.); these glycans can be insoluble or water-soluble.
evidence level4
citationLo Galiana (2026)
sourceMetabolism of β -mannans by representative, understudied Bacillota species from the human colon
topicKonjac Glucomannan Gut Health Randomized Trial
claim2016 2009 2012 2013 2015 2003 2025 2009 2011 2017 2015 2017 2016 The human gastrointestinal tract hosts a dense and complex microbial ecosystem (Sender et al.), with most bacteria belonging to the Bacillota and Bacteroidetes phyla and lower numbers belonging to the Actinobacteria, Proteobacteria and Verrucomicrobia phyla (Tap et al., The Human Microbiome Project Consortium, Duncan and Flint).
evidence level4
citationLo Galiana (2026)
sourceMetabolism of β -mannans by representative, understudied Bacillota species from the human colon

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Source documents

  1. Interaction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health
  2. Metabolism of β -mannans by representative, understudied Bacillota species from the human colon