topicKiwi Constipation Randomized Trial
claimSignificant improvements in overall IBS symptom severity were observed ( P P P P P P Conclusion While further research is needed, this is a promising first report that enzymatic digestion may have the potential to decrease the burden of disorders of the gut-brain interaction, including IBS.
evidence level3
citationKaye AJ (2026)
sourceFODMAP-Targeting Digestive Enzyme Blend for Management of Gastrointestinal Symptoms: A "Real-World" Pre-Post Intervention Cohort Study.
topicKiwi Constipation Randomized Trial
claimBackground and aims Irritable bowel syndrome (IBS) is a highly prevalent and morbid condition that causes tremendous symptom burden, impacts quality of life, and generates substantial healthcare costs.
evidence level3
citationKaye AJ (2026)
sourceFODMAP-Targeting Digestive Enzyme Blend for Management of Gastrointestinal Symptoms: A "Real-World" Pre-Post Intervention Cohort Study.
topicKiwi Constipation Randomized Trial
claimCurrent therapies are challenging to utilize and do not provide relief to many patients, creating a clear need for new innovation.
evidence level3
citationKaye AJ (2026)
sourceFODMAP-Targeting Digestive Enzyme Blend for Management of Gastrointestinal Symptoms: A "Real-World" Pre-Post Intervention Cohort Study.
topicKiwi Constipation Randomized Trial
claimAmong dietary interventions, the most consistent clinical evidence supports the use of soluble fiber (e.g., psyllium), kiwifruit or prunes, and magnesium- or sulfate-rich mineral waters to improve stool frequency and consistency.
evidence level4
citationRibichini E (2026)
sourceDietary strategies for chronic constipation: smartly targeting hormonal and reflex pathways for optimal recovery.
topicKiwi Constipation Randomized Trial
claimChronic constipation (CC) is a common disorder of gut-brain interaction that markedly impairs quality of life and remains challenging to manage.
evidence level4
citationRibichini E (2026)
sourceDietary strategies for chronic constipation: smartly targeting hormonal and reflex pathways for optimal recovery.
topicKiwi Constipation Randomized Trial
claimDespite the availability of laxatives and prosecretory agents, up to half of patients experience suboptimal relief, underscoring the need for complementary, physiology-based nutritional strategies.
evidence level4
citationRibichini E (2026)
sourceDietary strategies for chronic constipation: smartly targeting hormonal and reflex pathways for optimal recovery.