topicKetone Supplements Exercise Performance Randomized Trial
claimRecent evidence also suggests improvements in cognitive performance during exercise, including focus and reaction time, especially with exogenous ketone esters [].
evidence level3
citationSiri Morvarid (2025)
sourceThe science of ketogenic supplements for athletes: boosting endurance, efficiency, and energy metabolism
topicKetone Supplements Exercise Performance Randomized Trial
claimIn addition, it critically examines the available evidence on the long-term safety of these supplements in athletic populations, highlighting both their advantages and limitations.
evidence level3
citationSiri Morvarid (2025)
sourceThe science of ketogenic supplements for athletes: boosting endurance, efficiency, and energy metabolism
topicKetone Supplements Exercise Performance Randomized Trial
claimRecent findings also suggest that exogenous ketones support redox balance and reduce oxidative stress, contributing to improved endurance efficiency and faster post-exercise recovery.
evidence level3
citationSiri Morvarid (2025)
sourceThe science of ketogenic supplements for athletes: boosting endurance, efficiency, and energy metabolism
topicKetone Supplements Exercise Performance Randomized Trial
claim1 2 3 Use of supplements to enhance sporting performance is presently common among sportsmen and women, as well as sport enthusiasts [].
evidence level3
citationSiri Morvarid (2025)
sourceThe science of ketogenic supplements for athletes: boosting endurance, efficiency, and energy metabolism
topicKetone Supplements Exercise Performance Randomized Trial
claimGiven that the overall evidence base at present demonstrates little benefit for acute ingestion of EKS on tests of exercise capacity and performance [], this review instead describes the rationale and potential mechanistic basis for the proposed and emerging effects of EKS on recovery from exercise and adaptations to exercise training, as well as critically appraising the emerging literature in this field.
evidence level4
citationEgan Brendan (2025)
sourceAcute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review
topicKetone Supplements Exercise Performance Randomized Trial
claimHowever, a recent finding suggests that the time frame in which this effect is observed (typically 3–6 h) influences that conclusion, and that when the time frame is extended to 12 h, a bolus of 100 g produces a greater MPS response than 25 g [].
evidence level4
citationEgan Brendan (2025)
sourceAcute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review
topicKetone Supplements Exercise Performance Randomized Trial
claimCompared to thecontrol (CON) condition, glucose uptake was increased by 32% during the clamp, and skeletal muscle glycogen concentration was ~50% greater in the R‐βHB KME condition when measured post‐clamp i.e., after 2 h of recovery.
evidence level4
citationEgan Brendan (2025)
sourceAcute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review
topicKetone Supplements Exercise Performance Randomized Trial
claim1 2 3 4 5 6 7 1 7 7 The ketone bodies (KBs) acetoacetate (AcAc) and β‐hydroxybutyrate (βHB) are lipid‐derived, water‐soluble organic compounds produced almost exclusively in the liver, and whose production is amplified most obviously during physiological states characterized by low carbohydrate (CHO) availability i.e., prolonged fasting, starvation, or adherence to ketogenic diets [,,].
evidence level4
citationEgan Brendan (2025)
sourceAcute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review