topicKetone Ester Exercise Performance Randomized Trial
claimDuring altitude training camps, nocturnal hypoxic exposure is considered essential for inducing favorable physiological adaptations in the longer term such as increased hemoglobin mass and maximal oxygen consumption rates, which may ultimately improve endurance exercise performance ().
evidence level4
citationSTALMANS MYRTHE (2025)
sourceA Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance
topicKetone Ester Exercise Performance Randomized Trial
claimThis is generally accompanied by an increased wakefulness after sleep onset (WASO) (–,).
evidence level4
citationSTALMANS MYRTHE (2025)
sourceA Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance
topicKetone Ester Exercise Performance Randomized Trial
claimFor the LT determination, initial workload was set at 70 W and increased by 40 W per 8 min.
evidence level4
citationSTALMANS MYRTHE (2025)
sourceA Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance
topicKetone Ester Exercise Performance Randomized Trial
claim1 2 3 4 5 Sleeping at altitude is highly common in athletes as an integral part of altitude training camps ().
evidence level4
citationSTALMANS MYRTHE (2025)
sourceA Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance
topicKetone Ester Exercise Performance Randomized Trial
claimResults The ketone ester increased the time that participants were able to sustain an 80 rpm cycling cadence by 24 ± 9% ( p = 0.027).
evidence level4
citationNorwitz NG (2020)
sourceA Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.
topicKetone Ester Exercise Performance Randomized Trial
claimCorrespondingly, the ketone ester increased β-hydroxybutyrate levels to >3 mmol/L and decreased respiratory exchange ratio, consistent with a shift away from carbohydrate-dependent metabolism.
evidence level4
citationNorwitz NG (2020)
sourceA Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.
topicKetone Ester Exercise Performance Randomized Trial
claimConclusion Ketone ester supplementation improved endurance exercise performance in persons with Parkinson's disease and may, therefore, be useful as an adjunctive therapy to enhance the effectiveness of exercise treatment for Parkinson's disease.
evidence level4
citationNorwitz NG (2020)
sourceA Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.
topicKetone Ester Exercise Performance Randomized Trial
claimObjectives Routine exercise is thought to be among the only disease-modifying treatments for Parkinson's disease; however, patients' progressive loss of physical ability limits its application.
evidence level4
citationNorwitz NG (2020)
sourceA Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.