evidence table

Inulin Gut Comfort Randomized Trial Evidence Table

Structured evidence table for Inulin Gut Comfort Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Inulin Gut Comfort Randomized TrialIt is postulated that, apart from genetic predisposition, the rise of local and systemic immune response in PS could be a consequence of intestinal dysbiosis associated with increased intestinal permeability.2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Inulin Gut Comfort Randomized TrialWe expect that the RCT results will enable the introduction of personalised dietary therapy with prebiotic ITFs, which, unlike other PS therapies, would not pose a high risk of side effects.2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Inulin Gut Comfort Randomized TrialBACKGROUND: A strong, bidirectional association exists between gastrointestinal health and skin homeostasis in many chronic skin inflammations, including psoriasis (PS).2Krupa-Kozak U (2026)INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
Inulin Gut Comfort Randomized TrialIt identified practical strategies based on their potential interactions for combination therapy to mitigate gastrointestinal adverse effects, improved durability after drug withdrawal, and proposed testable hypotheses for precision fiber selection during and after GLP-1RA therapy.4Wang Yuxin (2026)Dietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
Inulin Gut Comfort Randomized TrialConventional management has largely relied on lifestyle modification, particularly caloric restriction and increased physical activity.4Wang Yuxin (2026)Dietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
Inulin Gut Comfort Randomized TrialAt present, such bidirectional interactions should be regarded as conceptual, hypothesis-generating frameworks rather than evidence-based treatment strategies.4Wang Yuxin (2026)Dietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
Inulin Gut Comfort Randomized TrialThis review uniquely synthesized mechanisms linking GLP-1 receptor agonists and dietary fibers through the gut–brain axis, microbiota-derived metabolites, and immune modulation.4Wang Yuxin (2026)Dietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
topicInulin Gut Comfort Randomized Trial
claimIt is postulated that, apart from genetic predisposition, the rise of local and systemic immune response in PS could be a consequence of intestinal dysbiosis associated with increased intestinal permeability.
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicInulin Gut Comfort Randomized Trial
claimWe expect that the RCT results will enable the introduction of personalised dietary therapy with prebiotic ITFs, which, unlike other PS therapies, would not pose a high risk of side effects.
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicInulin Gut Comfort Randomized Trial
claimBACKGROUND: A strong, bidirectional association exists between gastrointestinal health and skin homeostasis in many chronic skin inflammations, including psoriasis (PS).
evidence level2
citationKrupa-Kozak U (2026)
sourceINulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
topicInulin Gut Comfort Randomized Trial
claimIt identified practical strategies based on their potential interactions for combination therapy to mitigate gastrointestinal adverse effects, improved durability after drug withdrawal, and proposed testable hypotheses for precision fiber selection during and after GLP-1RA therapy.
evidence level4
citationWang Yuxin (2026)
sourceDietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
topicInulin Gut Comfort Randomized Trial
claimConventional management has largely relied on lifestyle modification, particularly caloric restriction and increased physical activity.
evidence level4
citationWang Yuxin (2026)
sourceDietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
topicInulin Gut Comfort Randomized Trial
claimAt present, such bidirectional interactions should be regarded as conceptual, hypothesis-generating frameworks rather than evidence-based treatment strategies.
evidence level4
citationWang Yuxin (2026)
sourceDietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control
topicInulin Gut Comfort Randomized Trial
claimThis review uniquely synthesized mechanisms linking GLP-1 receptor agonists and dietary fibers through the gut–brain axis, microbiota-derived metabolites, and immune modulation.
evidence level4
citationWang Yuxin (2026)
sourceDietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control

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Source documents

  1. INulin-type β-fructans supplementation to modulate gut microbiota and assessment of its effects on health status and GUT-SKIN axis parameters in patients with psoriasis (INGUTSKIN): the 8-week, randomised, double-blind, placebo-controlled clinical study protocol.
  2. Dietary Fiber and Glucagon-Like Peptide-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control