topicInulin Constipation Randomized Trial
claimAlterations in gut microbiota composition have been associated with hard stools and slow intestinal transit times [,].
evidence level2
citationPuhlmann Marie-Luise (2025)
sourceInulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study
topicInulin Constipation Randomized Trial
claimNotably, individuals diagnosed with functional constipation according to the Rome III criteria, were shown to have reduced relative abundances of butyrate-producing taxa in their fecal samples compared to healthy controls [].
evidence level2
citationPuhlmann Marie-Luise (2025)
sourceInulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study
topicInulin Constipation Randomized Trial
claimAdditionally, osmotic laxatives, a common pharmacological treatment for functional constipation, have been associated with reduced butyrate-producing taxa [].
evidence level2
citationPuhlmann Marie-Luise (2025)
sourceInulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study
topicInulin Constipation Randomized Trial
claim1 2 3 6 7 8 1 9 10 1 11 2 11 4 Functional constipation is a disorder affecting individuals of all ages.
evidence level2
citationPuhlmann Marie-Luise (2025)
sourceInulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study
topicInulin Constipation Randomized Trial
claimIn particular, it may be effective in the management of conditions such as hypertension, diabetes, and liver disease, alongside other potential health benefits, such as its ability to support gastrointestinal health, cardiovascular risk reduction, and metabolic control.
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicInulin Constipation Randomized Trial
claimStudies also emphasize its various metabolic and hepatoprotective effects, including the modulation of bile acid metabolism and the activation of pathways associated with the farnesoid X receptor.
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicInulin Constipation Randomized Trial
claimIn an animal study conducted with rats, psyllium was found to have antioxidant and anti-inflammatory effects [].
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicInulin Constipation Randomized Trial
claimPlantago ovata 1 2 3 4 5 The shells or husks ofseeds, also known as psyllium, ispaghula, or isabgol, are attracting attention in recent years due to their health benefits [,].
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke