evidence table
Inositol Pcos Randomized Trial Evidence Table
Structured evidence table for Inositol Pcos Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Inositol Pcos Randomized Trial | The global prevalence of PCOS increased from 36.7 to 69.5 million between 1990 and 2021. | 3 | Subakathulla Sumayyah (2026) | Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails? |
| Inositol Pcos Randomized Trial | Emerging evidence underscores that OS is not a mere byproduct of metabolic imbalance but a central driver that disrupts insulin signaling, amplifies androgen biosynthesis, and impairs folliculogenesis (,). | 3 | Subakathulla Sumayyah (2026) | Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails? |
| Inositol Pcos Randomized Trial | Low-dose variants of OCPs have been observed with an increased risk of myocardial infarction and cardiovascular arterial disease (). | 3 | Subakathulla Sumayyah (2026) | Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails? |
| Inositol Pcos Randomized Trial | 1 2 3 4 5 Polycystic ovary syndrome (PCOS) represents one of the most complex endocrine-metabolic disorders affecting women of reproductive age, characterized by a collection of reproductive, metabolic, and psychological manifestations (,). | 3 | Subakathulla Sumayyah (2026) | Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails? |
| Inositol Pcos Randomized Trial | 1 2 3 4 Polycystic ovary syndrome (PCOS) is among the most frequent endocrine disorders in women of reproductive age and is strongly associated with multiple cardiometabolic disturbances. | 4 | Muacevic Alexander (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review |
| Inositol Pcos Randomized Trial | While these approaches can reduce symptoms, they mostly do not address the underlying endocrine or metabolic disturbances and may be associated with adverse effects, including gastrointestinal discomfort, weight gain, and fatigue [,]. | 4 | Muacevic Alexander (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review |
| Inositol Pcos Randomized Trial | Increasing evidence also points to the benefits of curcumin, a polyphenolic compound from turmeric, which down-regulates inflammatory mediators and oxidative stress, thereby improving insulin action []. | 4 | Muacevic Alexander (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review |
| Inositol Pcos Randomized Trial | Globally, the condition affects roughly 4-20% of women, underscoring its significance as a public-health concern [,]. | 4 | Muacevic Alexander (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review |
Source documents