Structured evidence table for Inositol Metabolic Markers Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Inositol Metabolic Markers Randomized Trial | Metabolomics analysis revealed changes in metabolite levels, including increased aspartic acid and phosphocholine and reduced alanine, glutamate, and myo-inositol. | 4 | Chirico M (2026) | NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells. |
| Inositol Metabolic Markers Randomized Trial | Exploratory lipid analyses, suggested increased fatty acid and triacylglycerol content together with a higher PUFA/MUFA ratio. | 4 | Chirico M (2026) | NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells. |
| Inositol Metabolic Markers Randomized Trial | Conclusion These findings provide a descriptive metabolic characterization of DPSC neural commitment and identify candidate metabolite changes associated with early neural differentiation. | 4 | Chirico M (2026) | NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells. |
| Inositol Metabolic Markers Randomized Trial | Background Mesenchymal stem cells, particularly those derived from dental pulp cells (DPSCs), hold promising potential for neuro-regenerative therapies due to their multipotency and accessibility. | 4 | Chirico M (2026) | NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells. |
| Inositol Metabolic Markers Randomized Trial | Exercise increased cortical levels of lactic acid, creatine, taurine, and other metabolites involved in glycolysis, the TCA cycle, and osmoregulation, while SD disrupted energy-related metabolites and increased glial markers such as myo-inositol. | 4 | Silva BRDD (2026) | 1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice. |
| Inositol Metabolic Markers Randomized Trial | Sleep deprivation induces profound metabolic disturbances in the brain, while regular physical exercise is recognized for promoting neuroprotection and energy balance. | 4 | Silva BRDD (2026) | 1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice. |
| Inositol Metabolic Markers Randomized Trial | This study investigated the effects of chronic treadmill exercise on the cortical and hippocampal metabolic profiles of sleep-deprived Swiss mice using the entire 1H-NMR spectrum. | 4 | Silva BRDD (2026) | 1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice. |
Source documents