topicInositol Insulin Resistance Randomized Trial
claimBackground/Objectives : A 90-day randomized double-blind and placebo-controlled study was conducted to assess the effect of carob ( Ceratonia siliqua L.) on glucose metabolism in subjects with confirmed prediabetes.
evidence level2
citationPérez-Piñero S (2026)
sourceEffects of Specific Carob (<i>Ceratonia siliqua</i> L.) Liquid Concentrate on Glucose Metabolism in Subjects with Prediabetes: A Randomized Double-Blind Controlled Clinical Trial.
topicInositol Insulin Resistance Randomized Trial
claimMethods : The carob liquid concentrate containing inositols of the carob fruit (D-pinitol, myo-inositol, D-chiro inositol) was administered at a daily dose of 6.66 g, divided into two doses of 3.33 g each.
evidence level2
citationPérez-Piñero S (2026)
sourceEffects of Specific Carob (<i>Ceratonia siliqua</i> L.) Liquid Concentrate on Glucose Metabolism in Subjects with Prediabetes: A Randomized Double-Blind Controlled Clinical Trial.
topicInositol Insulin Resistance Randomized Trial
claim1 2 3 4 Polycystic ovary syndrome (PCOS) is among the most frequent endocrine disorders in women of reproductive age and is strongly associated with multiple cardiometabolic disturbances.
evidence level4
citationMuacevic Alexander (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review
topicInositol Insulin Resistance Randomized Trial
claimWhile these approaches can reduce symptoms, they mostly do not address the underlying endocrine or metabolic disturbances and may be associated with adverse effects, including gastrointestinal discomfort, weight gain, and fatigue [,].
evidence level4
citationMuacevic Alexander (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review
topicInositol Insulin Resistance Randomized Trial
claimIncreasing evidence also points to the benefits of curcumin, a polyphenolic compound from turmeric, which down-regulates inflammatory mediators and oxidative stress, thereby improving insulin action [].
evidence level4
citationMuacevic Alexander (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review
topicInositol Insulin Resistance Randomized Trial
claimGlobally, the condition affects roughly 4-20% of women, underscoring its significance as a public-health concern [,].
evidence level4
citationMuacevic Alexander (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review