topicHMB Resistance Exercise Meta-Analysis
claimThe Grading of Recommendations Assessment, Development, and Evaluation, Tool for the assEssment of Study qualiTy and reporting in EXercise, Rob 2, and Preferred Reporting Items for Systematic reviews and Meta-Analyses tools were used to evaluate the methodological quality and certainty of evidence.
evidence level1
citationHernandez-Martinez J (2026)
sourceCombined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.
topicHMB Resistance Exercise Meta-Analysis
claimFour overall meta-analysis showed significant increases (P Conclusion ST combined with WP or HMB supplementation may contribute to improvements in fat-free mass and selected physical performance outcomes in older people with sarcopenia.
evidence level1
citationHernandez-Martinez J (2026)
sourceCombined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.
topicHMB Resistance Exercise Meta-Analysis
claimHowever, the limited number of RCTs, relatively small sample sizes, moderate-to-high risk of bias, and inconsistent subgroup findings indicate that the current evidence should be interpreted cautiously and considered promising rather than definitive.
evidence level1
citationHernandez-Martinez J (2026)
sourceCombined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.
topicHMB Resistance Exercise Meta-Analysis
claimBackground Although previous studies have reported the benefits of combining physical activity with supplementation on body composition and physical performance in older people with sarcopenia, previous meta-analysis often included heterogeneous interventions, combining multiple types of supplements.
evidence level1
citationHernandez-Martinez J (2026)
sourceCombined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.