topicHmb Muscle Performance Randomized Trial
claimConclusion Acute post-exercise HMB-FA supplementation in elite judo athletes did not significantly influence muscle damage or oxidative stress markers but transiently increased antioxidant enzyme activities (CAT, GPX, and SOD).
evidence level2
citationTayebi SM (2026)
sourceEffects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.
topicHmb Muscle Performance Randomized Trial
claimPurpose High-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery.
evidence level2
citationTayebi SM (2026)
sourceEffects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.
topicHmb Muscle Performance Randomized Trial
claimThis randomized, double-blind, placebo-controlled pilot trial examined whether acute β -hydroxy- β -methylbutyrate free acid (HMB-FA) supplementation influences muscle damage, oxidative stress, and antioxidant biomarkers in elite judoka.
evidence level2
citationTayebi SM (2026)
sourceEffects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.
topicHmb Muscle Performance Randomized Trial
claimSurprisingly, 40 g whey did not maximize the anabolic response in older women, and HMB further increased the MPS feeding response to protein.
evidence level2
citationSmith K (2026)
sourceThe Effect of β-Hydroxy-β-Methyl Butyrate (HMB) upon Acute Fed-State Muscle Protein Turnover in Older Men and Women: A Randomized Double-Blind Controlled Crossover Clinical Trial.
topicHmb Muscle Performance Randomized Trial
claimBackground/Objectives : Anabolic resistance is thought to underlie muscle loss in sarcopenia.
evidence level2
citationSmith K (2026)
sourceThe Effect of β-Hydroxy-β-Methyl Butyrate (HMB) upon Acute Fed-State Muscle Protein Turnover in Older Men and Women: A Randomized Double-Blind Controlled Crossover Clinical Trial.
topicHmb Muscle Performance Randomized Trial
claimHere, we investigated the adjuvant role of beta-hydroxy-beta-methylbutyrate (HMB), a leucine metabolite, on the acute muscle anabolic response to oral protein supplementation in older adults.
evidence level2
citationSmith K (2026)
sourceThe Effect of β-Hydroxy-β-Methyl Butyrate (HMB) upon Acute Fed-State Muscle Protein Turnover in Older Men and Women: A Randomized Double-Blind Controlled Crossover Clinical Trial.