Structured evidence table for Hesperidin Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hesperidin Exercise Performance Randomized Trial | Endothelial dysfunction (ED) can lead to a reduced NO availability or an increased ET-1 synthesis, release, or activity [,]. | 3 | Imperatrice Maria (2022) | Hesperidin Functions as an Ergogenic Aid by Increasing Endothelial Function and Decreasing Exercise-Induced Oxidative Stress and Inflammation, Thereby Contributing to Improved Exercise Performance |
| Hesperidin Exercise Performance Randomized Trial | The main mechanisms underlying the pathophysiology of ED are increased reactive oxygen species (ROS), inflammation and diminished NO production, and bioavailability []. | 3 | Imperatrice Maria (2022) | Hesperidin Functions as an Ergogenic Aid by Increasing Endothelial Function and Decreasing Exercise-Induced Oxidative Stress and Inflammation, Thereby Contributing to Improved Exercise Performance |
| Hesperidin Exercise Performance Randomized Trial | Therefore, improved muscle perfusion during exercise via vascular endothelial function can positively impact endurance exercise performance. | 3 | Imperatrice Maria (2022) | Hesperidin Functions as an Ergogenic Aid by Increasing Endothelial Function and Decreasing Exercise-Induced Oxidative Stress and Inflammation, Thereby Contributing to Improved Exercise Performance |
| Hesperidin Exercise Performance Randomized Trial | 1 2 During exercise, skeletal muscle cells convert biological fuel (e.g., lipids, carbohydrates) into mechanical force to allow muscle contraction and therefore movement. | 3 | Imperatrice Maria (2022) | Hesperidin Functions as an Ergogenic Aid by Increasing Endothelial Function and Decreasing Exercise-Induced Oxidative Stress and Inflammation, Thereby Contributing to Improved Exercise Performance |
| Hesperidin Exercise Performance Randomized Trial | The use of ergogenic aids, particularly polyphenols such as 2S-hesperidin, has gained attention due to their potential to enhance exercise performance, although evidence in team sports and female athletes remains limited. | 4 | Flórez-Gil E (2026) | Acute Effects of 2S-Hesperidin Supplementation on Performance and External Load in Female Basketball Players. |
| Hesperidin Exercise Performance Randomized Trial | Overall, the observed pattern suggests that acute 2S-hesperidin supplementation may be associated with selected neuromuscular and intermittent performance responses, without clear changes in external load. | 4 | Flórez-Gil E (2026) | Acute Effects of 2S-Hesperidin Supplementation on Performance and External Load in Female Basketball Players. |
| Hesperidin Exercise Performance Randomized Trial | Given the small sample size and multiplicity of outcomes, these findings should be regarded as exploratory and hypothesis-generating rather than as confirmatory evidence of an ergogenic effect. | 4 | Flórez-Gil E (2026) | Acute Effects of 2S-Hesperidin Supplementation on Performance and External Load in Female Basketball Players. |
| Hesperidin Exercise Performance Randomized Trial | This study aimed to investigate the acute effects of 2S-hesperidin (Cardiose ® ) supplementation on physical performance and external and internal load during basketball-specific activity in female basketball players. | 4 | Flórez-Gil E (2026) | Acute Effects of 2S-Hesperidin Supplementation on Performance and External Load in Female Basketball Players. |
Source documents