topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claimThe current systematic review and meta-analysis study aimed to establish the effects of green tea supplementation on cardiovascular risk factors including lipid profile, blood pressure, glycemic control markers and CRP.
evidence level1
citationZamani M (2023)
sourceThe effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claimMethods A systematic literature search of randomized clinical trials (RCTs) that investigated the effects of green tea supplementation and cardiovascular risk factors was undertaken in online databases including PubMed/Medline, Scopus, Web of Science, and Embase using a combination of green tea and cardiovascular risk factors search terms.
evidence level1
citationZamani M (2023)
sourceThe effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claimResults from the random effects meta-analysis showed that GTE supplementation significantly reduced TC (WMD = -7.62; 95% CI: -10.51, -4.73; P = P = P = P = 0.008), DBP (WMD = -0.87; 95% CI: -1.45, -0.29; P = 0.003), while increasing HDL-C (WMD = 1.85; 95% CI: 0.87, 2.84; P = 0.010).
evidence level1
citationZamani M (2023)
sourceThe effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claimPurpose A bulk of observational studies have revealed the protective role of green tea supplementation in cardiovascular diseases.
evidence level1
citationZamani M (2023)
sourceThe effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claim1 Metabolic syndrome (MetS) is a multifactorial disorder characterized by a cluster of metabolic and cardiovascular abnormalities, including central obesity, dyslipidemia, insulin resistance, and hypertension, which collectively increase the risk of suffering from metabolic diseases such as type 2 diabetes and cardiovascular diseases in the long term [].
evidence level4
citationde la Fuente-Muñoz Mario (2026)
sourceEnhanced Effects of Complex Tea Extract and the Postbiotic BPL1 ® HT on Ameliorating the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claimImpairment at any step, such as decreased IRS phosphorylation or PI3K/Akt activity, leads to defective glucose transport, reduced glycogen synthesis, increased lipolysis, and the development of insulin resistance [].
evidence level4
citationde la Fuente-Muñoz Mario (2026)
sourceEnhanced Effects of Complex Tea Extract and the Postbiotic BPL1 ® HT on Ameliorating the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claim6 7 8 9 10 11 One of the most important factors contributing to the development of insulin resistance is increased adiposity, and particularly visceral adiposity [], a condition that is present in most patients with MetS [].
evidence level4
citationde la Fuente-Muñoz Mario (2026)
sourceEnhanced Effects of Complex Tea Extract and the Postbiotic BPL1 ® HT on Ameliorating the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice
topicGreen Tea Extract Cardiometabolic Markers Randomized Trial
claim2 3 4 5 Central to the pathogenesis of MetS is insulin resistance, a condition characterized by the disruption of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway, a critical mediator of insulin’s metabolic actions in key metabolic tissues such as liver, muscle, and adipose tissue [,].
evidence level4
citationde la Fuente-Muñoz Mario (2026)
sourceEnhanced Effects of Complex Tea Extract and the Postbiotic BPL1 ® HT on Ameliorating the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice