topicGrape Seed Extract Skin Hydration Meta-Analysis
claimBackground Nutrition is a modifiable factor in skin ageing, but its effects remain inconsistently quantified.
evidence level1
citationNg JY (2025)
sourceDietary interventions in skin ageing: a systematic review and meta-analysis.
topicGrape Seed Extract Skin Hydration Meta-Analysis
claimThis meta-analysis assessed human studies from the Web of Science on dietary intake and skin ageing, using pooled standardised mean differences (pSMD).
evidence level1
citationNg JY (2025)
sourceDietary interventions in skin ageing: a systematic review and meta-analysis.
topicGrape Seed Extract Skin Hydration Meta-Analysis
claimComplexation can improve active solubility and biocompatibility (for example, galangin/β-CD complexes improved aqueous compatibility and in vitro biocompatibility in oncology models) and has been exploited to stabilize plant-derived extracts such as carotenoids and propolis actives for downstream formulation and commercialization [,,].
evidence level3
citationMitrofan-Bandol Daniela-Ioana (2026)
sourceDecoding Cyclodextrins in Skin Applications: Structure, Mechanisms, and Safety in Cosmetic and Dermatologic Formulations (Part I)
topicGrape Seed Extract Skin Hydration Meta-Analysis
claimThe regulatory and safety landscape, therefore, demands case-by-case evaluation that couples physicochemical characterization, biocompatibility testing, and an awareness of manufacturing variables that influence both product performance and risk.
evidence level3
citationMitrofan-Bandol Daniela-Ioana (2026)
sourceDecoding Cyclodextrins in Skin Applications: Structure, Mechanisms, and Safety in Cosmetic and Dermatologic Formulations (Part I)
topicGrape Seed Extract Skin Hydration Meta-Analysis
claimRecent advances in mechanochemical and solvent-reduced syntheses (e.g., twin-screw extrusion) and in rational cross-linker selection aim to address scale-up and environmental sustainability while preserving functionality [,].
evidence level3
citationMitrofan-Bandol Daniela-Ioana (2026)
sourceDecoding Cyclodextrins in Skin Applications: Structure, Mechanisms, and Safety in Cosmetic and Dermatologic Formulations (Part I)
topicGrape Seed Extract Skin Hydration Meta-Analysis
claim1 2 1 3 4 3 5 Topical and transdermal delivery systems aim to deposit active ingredients into or across the integumentary system.
evidence level3
citationMitrofan-Bandol Daniela-Ioana (2026)
sourceDecoding Cyclodextrins in Skin Applications: Structure, Mechanisms, and Safety in Cosmetic and Dermatologic Formulations (Part I)