Structured evidence table for Grape Seed Extract Skin Aging Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Grape Seed Extract Skin Aging Randomized Trial | In addition, there is growing evidence that seed extracts benefit the intestinal microbiota, modulate lipid metabolism, and have antihypertensive activity, reinforcing their nutraceutical applicability []. | 3 | Fernandes Dayane Stéphanie (2026) | Fruit Seeds with Functional Applications: From Food Waste to Potential Uses |
| Grape Seed Extract Skin Aging Randomized Trial | The fruits selected for description in this study are widely consumed by various populations around the world, are used at an industrial scale, and, as a result, generate large-scale seed production, from which oils and bioactive compounds can be extracted for various applications in the cosmetic, pharmaceutical, and food industries. | 3 | Fernandes Dayane Stéphanie (2026) | Fruit Seeds with Functional Applications: From Food Waste to Potential Uses |
| Grape Seed Extract Skin Aging Randomized Trial | It should be noted that the quality of an oil is directly associated with its chemical composition, which depends on agronomic factors, climatic conditions, the variety and state of ripeness, technological factors related to extraction, such as the method and type of equipment used, as well as the conditions of harvesting, storage, and transportation of the product []. | 3 | Fernandes Dayane Stéphanie (2026) | Fruit Seeds with Functional Applications: From Food Waste to Potential Uses |
| Grape Seed Extract Skin Aging Randomized Trial | 1 2 3 Fruit processing, both on an industrial and domestic scale, results in the generation of solid waste which, when disposed of improperly, can cause considerable economic and environmental impacts []. | 3 | Fernandes Dayane Stéphanie (2026) | Fruit Seeds with Functional Applications: From Food Waste to Potential Uses |
| Grape Seed Extract Skin Aging Randomized Trial | Notably, the concentration of PIC required for certain in vitro activities remains higher than those typically achieved in vivo, and the current evidence base for PIC in human skin is considerably less developed than that for resveratrol. | 3 | Zhang Dian (2026) | Piceatannol from Passion Fruit Seed Waste: A Circular Bioeconomy-Driven Pathway Toward a Skin-Targeted Bioactive |
| Grape Seed Extract Skin Aging Randomized Trial | We aim to: (1) synthesize the evidence for PIC’s multi-target activity in skin aging and acne; (2) critically evaluate existing in vivo and clinical data to identify key evidence gaps; and (3) propose a phase-gate translational framework that prioritizes standardization, sustainable sourcing, nano-delivery, and clinical validation. | 3 | Zhang Dian (2026) | Piceatannol from Passion Fruit Seed Waste: A Circular Bioeconomy-Driven Pathway Toward a Skin-Targeted Bioactive |
| Grape Seed Extract Skin Aging Randomized Trial | Figure 3 Table 1 29 A robust body of in vitro and ex vivo evidence delineates PIC’s pleiotropic effects across the interconnected pathways driving skin aging and dysfunction, as summarized inand. | 3 | Zhang Dian (2026) | Piceatannol from Passion Fruit Seed Waste: A Circular Bioeconomy-Driven Pathway Toward a Skin-Targeted Bioactive |
| Grape Seed Extract Skin Aging Randomized Trial | Passiflora edulis 1 2 Figure 1 3 The global juice processing industry generates substantial quantities of passion fruit () seed waste, an agro-industrial byproduct that is often underutilized or discarded [,] (). | 3 | Zhang Dian (2026) | Piceatannol from Passion Fruit Seed Waste: A Circular Bioeconomy-Driven Pathway Toward a Skin-Targeted Bioactive |
Source documents