evidence table

Grape Seed Blood Pressure Randomized Trial Evidence Table

Structured evidence table for Grape Seed Blood Pressure Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Grape Seed Blood Pressure Randomized TrialSeverity, frequency and duration of migraine attacks, headache daily result (HDR), quality of life, migraine disability, mental health, anthropometric indices, blood pressure, and serum levels of calcitonin gene-related peptide (CGRP), vascular cell adhesion molecules-1, total antioxidant capacity, and malondialdehyde were measured at baseline and end of the trial.2Eshaghian N (2025)Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
Grape Seed Blood Pressure Randomized TrialConclusion This study provides evidence supporting the beneficial effects of GSE supplement on the serum levels of CGRP.2Eshaghian N (2025)Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
Grape Seed Blood Pressure Randomized TrialBackground The current study was conducted to assess the effect of grape seed extract (GSE) supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in migraine patients.2Eshaghian N (2025)Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
Grape Seed Blood Pressure Randomized TrialMaterials and methods In this randomized double-blinded controlled clinical trial, 50 patients with migraine were randomly allocated to receive either 200 mg/day GSE supplement ( n = 25) or placebo ( n = 25) for 8 weeks.2Eshaghian N (2025)Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
Grape Seed Blood Pressure Randomized TrialSignificant amounts of food waste come from fruit processing, causing economic and environmental impacts.4Fernandes DS (2026)Fruit Seeds with Functional Applications: From Food Waste to Potential Uses.
Grape Seed Blood Pressure Randomized TrialThe waste generated is a valuable source of compounds due to its concentration of nutrients, such as dietary fiber, vitamins, minerals, lipids with mono- and polyunsaturated fatty acids, and bioactive compounds.4Fernandes DS (2026)Fruit Seeds with Functional Applications: From Food Waste to Potential Uses.
topicGrape Seed Blood Pressure Randomized Trial
claimSeverity, frequency and duration of migraine attacks, headache daily result (HDR), quality of life, migraine disability, mental health, anthropometric indices, blood pressure, and serum levels of calcitonin gene-related peptide (CGRP), vascular cell adhesion molecules-1, total antioxidant capacity, and malondialdehyde were measured at baseline and end of the trial.
evidence level2
citationEshaghian N (2025)
sourceEffects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
topicGrape Seed Blood Pressure Randomized Trial
claimConclusion This study provides evidence supporting the beneficial effects of GSE supplement on the serum levels of CGRP.
evidence level2
citationEshaghian N (2025)
sourceEffects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
topicGrape Seed Blood Pressure Randomized Trial
claimBackground The current study was conducted to assess the effect of grape seed extract (GSE) supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in migraine patients.
evidence level2
citationEshaghian N (2025)
sourceEffects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
topicGrape Seed Blood Pressure Randomized Trial
claimMaterials and methods In this randomized double-blinded controlled clinical trial, 50 patients with migraine were randomly allocated to receive either 200 mg/day GSE supplement ( n = 25) or placebo ( n = 25) for 8 weeks.
evidence level2
citationEshaghian N (2025)
sourceEffects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
topicGrape Seed Blood Pressure Randomized Trial
claimSignificant amounts of food waste come from fruit processing, causing economic and environmental impacts.
evidence level4
citationFernandes DS (2026)
sourceFruit Seeds with Functional Applications: From Food Waste to Potential Uses.
topicGrape Seed Blood Pressure Randomized Trial
claimThe waste generated is a valuable source of compounds due to its concentration of nutrients, such as dietary fiber, vitamins, minerals, lipids with mono- and polyunsaturated fatty acids, and bioactive compounds.
evidence level4
citationFernandes DS (2026)
sourceFruit Seeds with Functional Applications: From Food Waste to Potential Uses.

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Source documents

  1. Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
  2. Fruit Seeds with Functional Applications: From Food Waste to Potential Uses.