evidence table

Glycerol Hydration Exercise Randomized Trial Evidence Table

Structured evidence table for Glycerol Hydration Exercise Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Glycerol Hydration Exercise Randomized TrialWhen added to water or sports drinks before exercise, glycerol has several benefits, including faster heart rate recovery (), enhanced body temperature regulation and reduced rectal temperature, particularly in hot and humid environments (); reduced perceived exertion (); and improved hydration levels (,).2Herrera-Amante Carlos Abraham (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
Glycerol Hydration Exercise Randomized TrialThese findings suggest limited and inconclusive evidence regarding glycerol’s impact on RE, highlighting the need for further investigation under controlled experimental conditions.2Herrera-Amante Carlos Abraham (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
Glycerol Hydration Exercise Randomized TrialVOpeak was measured using an incremental treadmill test (Pugh test), which started at 6 km/h and increased by 2 km/h every 3 min, with a constant 1% incline, until volitional exhaustion ().2Herrera-Amante Carlos Abraham (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
Glycerol Hydration Exercise Randomized Trial₃ ₈ ₃ 1 2 3 4 Glycerol, also known as 1,2,3-propanetriol or glycerin, is a three-carbon lipid-soluble molecule (CHO) that appears as a colorless, viscous, and hygroscopic liquid at room temperature that is capable of absorbing moisture from the environment ().2Herrera-Amante Carlos Abraham (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
Glycerol Hydration Exercise Randomized TrialCompared to G and CON, blood pH and blood bicarbonate concentration was significantly higher with G + SB and SB from 60-180 min (p Conclusions Fluid retention improved in G, SB and G + SB compared to CON, although there were no additive effects with G + SB compared to SB or G.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
Glycerol Hydration Exercise Randomized TrialIntroduction Background: It is unclear whether hyperhydration induced via glycerol, sodium bicarbonate or a combination of the two is most effective.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
Glycerol Hydration Exercise Randomized TrialAim: This study evaluated the effects of glycerol-, sodium bicarbonate-, and glycerol + sodium bicarbonate-induced hyperhydration on measures of fluid retention, blood buffering capacity, and gastrointestinal symptoms at rest, in comparison to a fluid-only control.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Hydration Exercise Randomized Trial
claimWhen added to water or sports drinks before exercise, glycerol has several benefits, including faster heart rate recovery (), enhanced body temperature regulation and reduced rectal temperature, particularly in hot and humid environments (); reduced perceived exertion (); and improved hydration levels (,).
evidence level2
citationHerrera-Amante Carlos Abraham (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
topicGlycerol Hydration Exercise Randomized Trial
claimThese findings suggest limited and inconclusive evidence regarding glycerol’s impact on RE, highlighting the need for further investigation under controlled experimental conditions.
evidence level2
citationHerrera-Amante Carlos Abraham (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
topicGlycerol Hydration Exercise Randomized Trial
claimVOpeak was measured using an incremental treadmill test (Pugh test), which started at 6 km/h and increased by 2 km/h every 3 min, with a constant 1% incline, until volitional exhaustion ().
evidence level2
citationHerrera-Amante Carlos Abraham (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
topicGlycerol Hydration Exercise Randomized Trial
claim₃ ₈ ₃ 1 2 3 4 Glycerol, also known as 1,2,3-propanetriol or glycerin, is a three-carbon lipid-soluble molecule (CHO) that appears as a colorless, viscous, and hygroscopic liquid at room temperature that is capable of absorbing moisture from the environment ().
evidence level2
citationHerrera-Amante Carlos Abraham (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
topicGlycerol Hydration Exercise Randomized Trial
claimCompared to G and CON, blood pH and blood bicarbonate concentration was significantly higher with G + SB and SB from 60-180 min (p Conclusions Fluid retention improved in G, SB and G + SB compared to CON, although there were no additive effects with G + SB compared to SB or G.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Hydration Exercise Randomized Trial
claimIntroduction Background: It is unclear whether hyperhydration induced via glycerol, sodium bicarbonate or a combination of the two is most effective.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Hydration Exercise Randomized Trial
claimAim: This study evaluated the effects of glycerol-, sodium bicarbonate-, and glycerol + sodium bicarbonate-induced hyperhydration on measures of fluid retention, blood buffering capacity, and gastrointestinal symptoms at rest, in comparison to a fluid-only control.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.

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Source documents

  1. Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial
  2. Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.