evidence table

Glucosamine Knee Osteoarthritis Randomized Trial Evidence Table

Structured evidence table for Glucosamine Knee Osteoarthritis Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Glucosamine Knee Osteoarthritis Randomized TrialBackground Osteoarthritis is a common joint disease, especially among individuals aged 50 and older, leading to symptoms such as pain, stiffness, and functional limitations, particularly in weight-bearing joints like the knees.2Čeh T (2026)Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
Glucosamine Knee Osteoarthritis Randomized TrialKnee osteoarthritis (KOA) is increasingly prevalent, making effective treatment strategies critical.2Čeh T (2026)Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
Glucosamine Knee Osteoarthritis Randomized TrialIt causes chronic pain, reduced mobility, and disability, affecting 607 million individuals worldwide, with nearly 46.6 million new cases annually [].4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Glucosamine Knee Osteoarthritis Randomized Trial11 12 13 14 15 11 15 HLA-DRB1 HLA-DQB1 Genetic polymorphisms in sterol regulatory element-binding protein 2 (rs2228314) [], interleukin-6 (rs1800795) [], and resistin (RETN) [] in Indian and Pakistani cohorts and growth differentiation factor 5 (rs143383) [],, andin Thai populations [] are linked to OA risk.4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Glucosamine Knee Osteoarthritis Randomized TrialNeed for expert opinion Despite growing clinical and mechanistic evidence for collagen supplementation in OA, several gaps and challenges remain in translating this knowledge into clinical practice, especially in the Indian subcontinent and Southeast Asia.4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Glucosamine Knee Osteoarthritis Randomized Trial1 2 3 4 6 7 8 9 10 1 Osteoarthritis (OA) is the most prevalent degenerative joint disease globally and the second most common rheumatologic condition [].4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicGlucosamine Knee Osteoarthritis Randomized Trial
claimBackground Osteoarthritis is a common joint disease, especially among individuals aged 50 and older, leading to symptoms such as pain, stiffness, and functional limitations, particularly in weight-bearing joints like the knees.
evidence level2
citationČeh T (2026)
sourceComplementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
topicGlucosamine Knee Osteoarthritis Randomized Trial
claimKnee osteoarthritis (KOA) is increasingly prevalent, making effective treatment strategies critical.
evidence level2
citationČeh T (2026)
sourceComplementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
topicGlucosamine Knee Osteoarthritis Randomized Trial
claimIt causes chronic pain, reduced mobility, and disability, affecting 607 million individuals worldwide, with nearly 46.6 million new cases annually [].
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicGlucosamine Knee Osteoarthritis Randomized Trial
claim11 12 13 14 15 11 15 HLA-DRB1 HLA-DQB1 Genetic polymorphisms in sterol regulatory element-binding protein 2 (rs2228314) [], interleukin-6 (rs1800795) [], and resistin (RETN) [] in Indian and Pakistani cohorts and growth differentiation factor 5 (rs143383) [],, andin Thai populations [] are linked to OA risk.
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicGlucosamine Knee Osteoarthritis Randomized Trial
claimNeed for expert opinion Despite growing clinical and mechanistic evidence for collagen supplementation in OA, several gaps and challenges remain in translating this knowledge into clinical practice, especially in the Indian subcontinent and Southeast Asia.
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicGlucosamine Knee Osteoarthritis Randomized Trial
claim1 2 3 4 6 7 8 9 10 1 Osteoarthritis (OA) is the most prevalent degenerative joint disease globally and the second most common rheumatologic condition [].
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion

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Source documents

  1. Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
  2. Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion