Structured evidence table for Glucomannan Dietary Fiber Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Glucomannan Dietary Fiber Meta-Analysis | Obesity is a globally prevalent metabolic disorder closely associated with gut microbiota dysbiosis. | 4 | Hu B (2026) | Gut <i>Enterococcus faecium</i> derived leucic acid mediates the antiobesity effect of dietary fiber. |
| Glucomannan Dietary Fiber Meta-Analysis | faecium or exogenous LEA supplementation improved obesity-associated metabolic phenotypes. | 4 | Hu B (2026) | Gut <i>Enterococcus faecium</i> derived leucic acid mediates the antiobesity effect of dietary fiber. |
| Glucomannan Dietary Fiber Meta-Analysis | Furthermore, using a high-content screening system and an in vitro fermentation model, we found that the dietary fiber glucomannan exerted anti-obesity effects by promoting the growth of E. | 4 | Hu B (2026) | Gut <i>Enterococcus faecium</i> derived leucic acid mediates the antiobesity effect of dietary fiber. |
| Glucomannan Dietary Fiber Meta-Analysis | However, the precise roles of gut microbiota and microbial metabolism in this disease remain unclear. | 4 | Hu B (2026) | Gut <i>Enterococcus faecium</i> derived leucic acid mediates the antiobesity effect of dietary fiber. |
| Glucomannan Dietary Fiber Meta-Analysis | Effects of OKGM on metabolic health was evaluated by a 13-week oral toxicity study in ICR mice, in compliance with OECD Guideline 408 (OECD, 1998). | 4 | Li Yao (2024) | Oxidized konjac glucomannan: A safe dietary fiber influencing mouse gut microbiota |
| Glucomannan Dietary Fiber Meta-Analysis | p Table S5 Garthoff et al., 2010 Jonker et al., 2010 Sakata, 1986 Jonker, Fowler, Albers, Tzoumaki, van het Hof, & Aparicio-Vergara, 2020 The relative weights of the empty caecum were found to be significantly higher in both male and female mice of the mid- and high-dose groups ( < 0.05) as compared to the control group (). | 4 | Li Yao (2024) | Oxidized konjac glucomannan: A safe dietary fiber influencing mouse gut microbiota |
| Glucomannan Dietary Fiber Meta-Analysis | Increased osmolarity of cecal contents and increased bulk of contents were some of the other potential mechanisms that could contribute to cecal enlargement (). | 4 | Li Yao (2024) | Oxidized konjac glucomannan: A safe dietary fiber influencing mouse gut microbiota |
| Glucomannan Dietary Fiber Meta-Analysis | Its structural backbone is characterized by β-1,4 glycosidic bonds, interlinking-mannose and-glucose units, and features an acetyl group at the C-6 position on roughly every 19th sugar unit (). | 4 | Li Yao (2024) | Oxidized konjac glucomannan: A safe dietary fiber influencing mouse gut microbiota |
Source documents