topicGinkgo Memory Randomized Trial
claimAburto et al., 2020 Gaspar-Silva et al., 2023 Maldonado Briegas et al., 2020 Life expectancy has increased markedly since the last century, leading to a rapidly expanding elderly population globally.
evidence level2
citationGao Yuhong (2026)
sourceCistanche tubulosa - Ginkgo biloba combination enhances memory via cortico-cerebellar reorganization: a randomized controlled trial
topicGinkgo Memory Randomized Trial
claimSimilarly, a meta-analysis of 23 RCTs found that creatine supplementation improved memory in healthy individuals, particularly in older adults aged 66–76 years ().
evidence level2
citationGao Yuhong (2026)
sourceCistanche tubulosa - Ginkgo biloba combination enhances memory via cortico-cerebellar reorganization: a randomized controlled trial
topicGinkgo Memory Randomized Trial
claim(5) portrait memory (PM): Participants memorized and later recalled details (name, occupation, preferences) associated with six portraits.
evidence level2
citationGao Yuhong (2026)
sourceCistanche tubulosa - Ginkgo biloba combination enhances memory via cortico-cerebellar reorganization: a randomized controlled trial
topicGinkgo Memory Randomized Trial
claimThis demographic shift underscores the urgent need to address age-related health challenges, particularly cognitive decline, as a critical public health priority ().
evidence level2
citationGao Yuhong (2026)
sourceCistanche tubulosa - Ginkgo biloba combination enhances memory via cortico-cerebellar reorganization: a randomized controlled trial
topicGinkgo Memory Randomized Trial
claimIn addition, an overview of systematic reviews synthesized the broader EGb 761 evidence base across indications and highlighted that conclusions require caution given the methodological limitations of many reviews [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Memory Randomized Trial
claimReal-world observational analyses have also reported associations between prescriptions of Ginkgo leaf extract and reduced risk of dementia severity progression, albeit with the inherent limitations of non-randomized designs [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Memory Randomized Trial
claimAccordingly, this review revisits the historical evidence base with explicit attention to heterogeneity and methodological design, and then examines biomarker-confirmed AD-spectrum studies as a potential pivot point.
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Memory Randomized Trial
claim1 2 Alzheimer’s disease (AD) remains the most common cause of dementia and continues to impose a major burden on patients, caregivers, and healthcare systems [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?