topicGinger Gut Health Randomized Trial
claim, , Among the numerous sources of dietary polyphenols, spices are the most concentrated food source of polyphenols with established roles in gut microbial modulation.One of the primary mechanisms of action of spice polyphenols is the result of bacterial metabolism and the production of metabolites such as short-chain fatty acids (SCFAs)—acetate, propionate, and butyrate.
evidence level3
citationCrowe-White Kristi M (2026)
sourceSpices for Targeting the Gut Microbiome to Improve Cardiometabolic Health
topicGinger Gut Health Randomized Trial
claimAs a result of this proliferation, enhancement in SCFA production was observed, with acetate increasing by 24% and butyrate by 19%.
evidence level3
citationCrowe-White Kristi M (2026)
sourceSpices for Targeting the Gut Microbiome to Improve Cardiometabolic Health
topicGinger Gut Health Randomized Trial
claimUsing the total cholesterol : high-density-lipoprotein cholesterol ratio (a robust clinical predictor of future cardiac events),our previously published findings suggest that consumption of cinnamon and ginger daily decreased the ratio by approximately 4.4%, thus reducing lipid-associated cardiovascular risk factors.
evidence level3
citationCrowe-White Kristi M (2026)
sourceSpices for Targeting the Gut Microbiome to Improve Cardiometabolic Health
topicGinger Gut Health Randomized Trial
claimMicrobial regulation of host metabolism is significantly impacted by the composition of the diet.
evidence level3
citationCrowe-White Kristi M (2026)
sourceSpices for Targeting the Gut Microbiome to Improve Cardiometabolic Health
topicGinger Gut Health Randomized Trial
claimIt has been suggested that health benefits associated with gingerols may be due to modification of the gut microbiome, especially in disease models.
evidence level4
citationMahalak KK (2026)
sourceThe ginger polyphenol 6-gingerol elicits minimal changes in an <i>ex vivo</i> human gut microbiome.
topicGinger Gut Health Randomized Trial
claimTo address this, the impact of 6-gingerol, the most abundant polyphenol found in ginger, on the gut microbiomes of four age groups (infants, children, adults (22-40), and adults (60+)) was determined using SIFR® technology.
evidence level4
citationMahalak KK (2026)
sourceThe ginger polyphenol 6-gingerol elicits minimal changes in an <i>ex vivo</i> human gut microbiome.
topicGinger Gut Health Randomized Trial
claimThis study found that, in healthy gut microbiota, 6-gingerol did not have a strong effect within a 24-h period of treatment.
evidence level4
citationMahalak KK (2026)
sourceThe ginger polyphenol 6-gingerol elicits minimal changes in an <i>ex vivo</i> human gut microbiome.
topicGinger Gut Health Randomized Trial
claimGinger ( Zingiber officinale ) has a long history of use in traditional medicine and the modern world to alleviate health conditions, particularly those related to indigestion and nausea.
evidence level4
citationMahalak KK (2026)
sourceThe ginger polyphenol 6-gingerol elicits minimal changes in an <i>ex vivo</i> human gut microbiome.