topicGarlic Lipid Profile Randomized Trial
claimPrediabetes is defined as an intermediate metabolic state characterized by impaired fasting glucose and/or impaired glucose tolerance, associated with a high risk of progression to diabetes and vascular dysfunction [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Lipid Profile Randomized Trial
claimHowever, long-term use of conventional antidiabetic agents has been associated with adverse effects, reduced tolerance, and diminished efficacy in certain populations [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Lipid Profile Randomized Trial
claim12 13 14 15 16 17 18 Aloe vera Evidence from both clinical studies (involving human participants) and preclinical studies (including in vivo and in vitro experimental models) indicates that several herbal medicines exhibit antihyperglycaemic effects through multiple biological mechanisms [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Lipid Profile Randomized Trial
claim1 2 3 4 5 6 7 8 9 8 10 11 Diabetes mellitus is a persistent metabolic condition characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both [].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Lipid Profile Randomized Trial
claimAlso, total cholesterol (TC) was significantly reduced (WMD: -8.26; 95% CI: -14.65 to -1.88; I ² = 90.9%) based on 7 effect sizes, while changes in HDL-C, TG, and LDL-C were not significant overall.
evidence level1
citationEbrahimzadeh A (2026)
sourceThe Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
topicGarlic Lipid Profile Randomized Trial
claimMoreover, longer duration of garlic supplementation significantly improved all lipid profiles in patients with T2DM.
evidence level1
citationEbrahimzadeh A (2026)
sourceThe Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
topicGarlic Lipid Profile Randomized Trial
claimBackground Garlic, as an additive, a spice, and an ancient herbal medicine, has been proposed as a potential treatment for type 2 diabetes mellitus (T2DM).
evidence level1
citationEbrahimzadeh A (2026)
sourceThe Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
topicGarlic Lipid Profile Randomized Trial
claimThis systematic review and meta-analysis provides a comprehensive evaluation of the effects of garlic supplementation on fasting blood sugar (FBS), hemoglobin A1c (HbA1c), and lipid profile in patients with T2DM.
evidence level1
citationEbrahimzadeh A (2026)
sourceThe Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.