topicGarlic Blood Glucose Randomized Trial
claimPrediabetes is defined as an intermediate metabolic state characterized by impaired fasting glucose and/or impaired glucose tolerance, associated with a high risk of progression to diabetes and vascular dysfunction [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Blood Glucose Randomized Trial
claimHowever, long-term use of conventional antidiabetic agents has been associated with adverse effects, reduced tolerance, and diminished efficacy in certain populations [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Blood Glucose Randomized Trial
claim12 13 14 15 16 17 18 Aloe vera Evidence from both clinical studies (involving human participants) and preclinical studies (including in vivo and in vitro experimental models) indicates that several herbal medicines exhibit antihyperglycaemic effects through multiple biological mechanisms [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Blood Glucose Randomized Trial
claim1 2 3 4 5 6 7 8 9 8 10 11 Diabetes mellitus is a persistent metabolic condition characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both [].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicGarlic Blood Glucose Randomized Trial
claimNational dietary guidelines from several countries (eg, the United States, United Kingdom, and Australia) recommend the consumption of spices to lower sodium intake.The National Institutes of Health (NIH)–funded Dietary Approaches to Stop Hypertension (DASH) healthy eating plan replaces salt with spices and herbs as a means to lower blood pressure without medication.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicGarlic Blood Glucose Randomized Trial
claimIt was also demonstrated that salt intake was associated with regional metabolic activity in the insula and orbitofrontal cortex (OFC) areas of the brain.The administration of capsaicin (chili pepper) in the Li et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicGarlic Blood Glucose Randomized Trial
claim(2013) To investigate whether spice (poly)phenols reduce GI and systemic formation of cytotoxic lipid peroxidation products and increase NO formation, thereby leading to improved endothelial vascular function n  = 11 men with type 2 diabetes RCT 2 test meals, 1 wk apart  Zhang et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicGarlic Blood Glucose Randomized Trial
claimHerbs and spices have been used in various countries around the world for centuries.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain