topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimConsequently, RCTs involving subjects with increased cardiometabolic risk may clarify the effects of EC and MX as cocoa components on cardiovascular health parameters.
evidence level2
citationWeigant J (2025)
sourceCardiometabolic Impact of Encapsulated Cocoa Powder and Pure Cocoa Ingredients Supplementation: A Comparative Placebo-Controlled RCT in Adults.
topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimConsuming cocoa rich in flavan-3-ols (particularly epicatechin [EC]) may reduce vascular stiffness and blood pressure (BP) and improve serum lipid profiles.
evidence level2
citationWeigant J (2025)
sourceCardiometabolic Impact of Encapsulated Cocoa Powder and Pure Cocoa Ingredients Supplementation: A Comparative Placebo-Controlled RCT in Adults.
topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimBecause interventional studies on pure EC exhibited inconclusive results, the role of other cocoa ingredients such as methylxanthines (MX) on vascular health was assumed.
evidence level2
citationWeigant J (2025)
sourceCardiometabolic Impact of Encapsulated Cocoa Powder and Pure Cocoa Ingredients Supplementation: A Comparative Placebo-Controlled RCT in Adults.
topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimSitting induces declines in endothelial function, increasing the risk of cardiovascular diseases.
evidence level4
citationDaniele A (2025)
sourceDietary flavanols preserve upper- and lower-limb endothelial function during sitting in high- and low-fit young healthy males.
topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimSitting significantly reduced FMD in the SFA and BA and increased diastolic BP in both fitness groups.
evidence level4
citationDaniele A (2025)
sourceDietary flavanols preserve upper- and lower-limb endothelial function during sitting in high- and low-fit young healthy males.
topicFlavanol-Rich Cocoa Blood Pressure Randomized Trial
claimSedentary behaviour is very prevalent in modern societies, with young adults spending approximately 6 h/day sitting.
evidence level4
citationDaniele A (2025)
sourceDietary flavanols preserve upper- and lower-limb endothelial function during sitting in high- and low-fit young healthy males.