exercise performance

Essential Amino Acids Muscle Protein Synthesis Randomized Trial Evidence Table

Name: Essential Amino Acids Muscle Protein Synthesis Randomized Trial Evidence Table
Creator: Migaku

Structured evidence table for Essential Amino Acids Muscle Protein Synthesis Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topic	claim	evidence level	citation	source
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	6 [13] [14] [15] 20 11 18 11 Sarcopenia and age-related decline in skeletal muscle mass and function are major determinants of frailty, disability, and reduced quality of life in older adults [,,,,].	2	Sumi Koichiro (2026)	Fasting plasma amino acid profiles after resistance exercise with or without nutritional supplementation in older adults: an exploratory analysis of secondary outcomes from a randomized controlled trial
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	The previously reported randomized controlled trial underlying the present work showed that low-dose dairy protein plus micronutrient supplementation during resistance exercise improved lean mass outcomes compared with exercise alone in community-dwelling older adults [].	2	Sumi Koichiro (2026)	Fasting plasma amino acid profiles after resistance exercise with or without nutritional supplementation in older adults: an exploratory analysis of secondary outcomes from a randomized controlled trial
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	2 22 19 11 Although intervention studies usually focus on body composition and physical performance, emerging evidence suggests that fasting plasma free amino acid profiles may provide complementary information on whole-body amino acid handling, muscle-related phenotypes, and nutritional status in older adults under relatively steady-state conditions [,].	2	Sumi Koichiro (2026)	Fasting plasma amino acid profiles after resistance exercise with or without nutritional supplementation in older adults: an exploratory analysis of secondary outcomes from a randomized controlled trial
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	Resistance exercise is a key strategy to preserve muscle health, and combined exercise-nutrition approaches are often more effective than exercise alone, although the certainty and magnitude of benefit vary across studies [,].	2	Sumi Koichiro (2026)	Fasting plasma amino acid profiles after resistance exercise with or without nutritional supplementation in older adults: an exploratory analysis of secondary outcomes from a randomized controlled trial
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	LEAA mixtures are defined here as oral supplements containing all nine indispensable amino acids with about 40% or more leucine by weight; studies of leucine-enriched branched-chain amino acids, free leucine, and leucine-enriched protein are treated as indirect evidence.	4	Nagao K (2026)	Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review.
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	Function improved when LEAA was combined with exercise, but exercise was given in all such trials, so the effect of LEAA alone is unclear.	4	Nagao K (2026)	Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review.
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	Evidence for long-term benefits that patients can feel is still limited, and safety has not been assessed systematically.	4	Nagao K (2026)	Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review.
Essential Amino Acids Muscle Protein Synthesis Randomized Trial	Muscle wasting driven by aging, chronic disease, or intensive exercise undermines mobility, metabolic health, and survival-yet the people who lose the most muscle are often those least able to eat more protein.	4	Nagao K (2026)	Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review.