Structured evidence table for Elderberry Upper Respiratory Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Elderberry Upper Respiratory Randomized Trial | Limited diversity of cultivatedimposes risks associated with increased vulnerability to phytopathogens and logistic challenges due to a narrow harvesting period (). | 4 | Boroduske Anete (2021) | Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S-protein RBD and hACE2 binding in vitro |
| Elderberry Upper Respiratory Randomized Trial | Underexplored wild germplasm ofalso implicates a risk in case of emergence of new previously unreported industrial applications because potentially superior genotypes are missed out. | 4 | Boroduske Anete (2021) | Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S-protein RBD and hACE2 binding in vitro |
| Elderberry Upper Respiratory Randomized Trial | Antiviral activity ofextracts has previously been associated with specific compounds belonging to flavonoids.proposed that flavonoid compounds ofberry extract - 5,7,3′,4′-tetra--methylquercetin and 5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)chroman-3-yl-3,4,5-trihydroxycyclohexanecarboxylate might be acting as inhibitors of viral binding to the host cell thus prevent viral entry. | 4 | Boroduske Anete (2021) | Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S-protein RBD and hACE2 binding in vitro |
| Elderberry Upper Respiratory Randomized Trial | nigra O O Atkinson and Atkinson, 2002 Charlebois et al., 2010 Bolli, 1994 Applequist, 2013 Tiralongo et al., 2016 Hawkins et al., 2019 Silva et al., 2017 Mota et al., 2020 Milena et al., 2019 is a medicinal tree native to western and southern parts of Europe and North Africa (). | 4 | Boroduske Anete (2021) | Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S-protein RBD and hACE2 binding in vitro |
| Elderberry Upper Respiratory Randomized Trial | The prospective, controlled study in humans found no increase in risk of major malformations. | 4 | Holst L (2014) | Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy? |
| Elderberry Upper Respiratory Randomized Trial | Over 2000 persons were given the treatment, but equal amounts of studies of good quality found positive and negative results. | 4 | Holst L (2014) | Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy? |
| Elderberry Upper Respiratory Randomized Trial | Due to lack of evidence of efficacy and safety, health care personnel should not advice pregnant women to use echinacea or elderberry against upper respiratory tract infection. | 4 | Holst L (2014) | Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy? |
| Elderberry Upper Respiratory Randomized Trial | Both herbs are commonly used to prevent or treat upper respiratory tract infections (URTIs) and surveys have shown that they are also used by pregnant women. | 4 | Holst L (2014) | Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy? |
Source documents