topicElderberry Immune Wellness Randomized Trial
claimA prospective cohort study of 428 couples in infertility clinics found that 29% of couples used a CAM modality for infertility treatment, with 17% specifically using herbal therapies over the course of 18 months ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicElderberry Immune Wellness Randomized Trial
claimConcurrent use of herbal medicines with prescription medications is reported among 20%–30% of prescription drug users in the United States; there is evidence via in vitro and in vivo studies that herbal therapies can act as metabolic inhibitors or inducers of prescription medications when used in combination ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicElderberry Immune Wellness Randomized Trial
claimRisks of herbal-drug interactions span from side effects (eg, bleeding, cardiotoxicity, hypoglycemia, hypotension) to altered pharmacokinetics (eg, decreased absorption, increased metabolism) of medications ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice
topicElderberry Immune Wellness Randomized Trial
claim1 1 2 3 4 The Center for Disease Control’s (CDC) 2017 National Health and Nutrition Examination Survey estimated that, on average, 57% of the United States population uses dietary supplements, with botanicals or “herbal supplements” comprising 5.1–8.3% of these supplements ().
evidence level4
citationFriedman Julie (2023)
sourceHerbal supplement use among reproductive-aged women in an academic infertility practice