topicElderberry Cold Duration Randomized Trial
claimDuring the COVID-19 pandemic, there has been interest in elderberry supplements to treat or prevent illness, but also concern that elderberry might overstimulate the immune system and increase the risk of 'cytokine storm'.
evidence level1
citationWieland LS (2021)
sourceElderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
topicElderberry Cold Duration Randomized Trial
claimWe aimed to determine benefits and harms of elderberry for the prevention and treatment of viral respiratory infections, and to assess the relationship between elderberry supplements and negative health impacts associated with overproduction of pro-inflammatory cytokines.
evidence level1
citationWieland LS (2021)
sourceElderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
topicElderberry Cold Duration Randomized Trial
claimTwo reviewers independently assessed studies for inclusion, extracted data from studies, assessed risk of bias using Cochrane tools, and evaluated certainty of estimates using GRADE.
evidence level1
citationWieland LS (2021)
sourceElderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
topicElderberry Cold Duration Randomized Trial
claimBackground Elderberry has traditionally been used to prevent and treat respiratory problems.
evidence level1
citationWieland LS (2021)
sourceElderberry for prevention and treatment of viral respiratory illnesses: a systematic review.
topicElderberry Cold Duration Randomized Trial
claimIntercontinental air travel can be stressful, especially for respiratory health.
evidence level2
citationTiralongo E (2016)
sourceElderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.
topicElderberry Cold Duration Randomized Trial
claimElderberries have been used traditionally, and in some observational and clinical studies, as supportive agents against the common cold and influenza.
evidence level2
citationTiralongo E (2016)
sourceElderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.