Structured evidence table for Cyanocobalamin Fatigue Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Cyanocobalamin Fatigue Randomized Trial | There is also the assumption that a water-soluble vitamin carries negligible risk [,]. | 3 | Yepes-Calderón Manuela (2026) | Vitamin B 12 Supplementation: Is More Always Better? |
| Cyanocobalamin Fatigue Randomized Trial | A critical appraisal is warranted to delineate evidence-based indications, clarify benefits and harms in replete populations, and guide prudent dosing and monitoring. | 3 | Yepes-Calderón Manuela (2026) | Vitamin B 12 Supplementation: Is More Always Better? |
| Cyanocobalamin Fatigue Randomized Trial | To investigate effects beyond deficiency correction, we examined evidence on vitamin Bpharmacokinetics and routes of administration, as well as studies assessing potential health benefits in non-deficient individuals. | 3 | Yepes-Calderón Manuela (2026) | Vitamin B 12 Supplementation: Is More Always Better? |
| Cyanocobalamin Fatigue Randomized Trial | 12 12 1 2 3 4 4 5 Vitamin Bsupplements are usually prescribed to cover deficiencies and, less frequently, as cofactor therapy for rare inborn errors of metabolism [,]. | 3 | Yepes-Calderón Manuela (2026) | Vitamin B 12 Supplementation: Is More Always Better? |
| Cyanocobalamin Fatigue Randomized Trial | Supplementation with B vitamins and magnesium improved fatigue and symptom-based disease activity scores in UC; however, effects on underlying inflammatory activity remain uncertain. | 4 | Ramezani E (2026) | Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease. |
| Cyanocobalamin Fatigue Randomized Trial | This study investigated the efficacy of supplementation with B vitamins and magnesium in alleviating fatigue, improving disease activity, and health-related quality of life (HRQoL) in patients with inflammatory bowel disease (IBD) based on patient-reported outcomes. | 4 | Ramezani E (2026) | Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease. |
| Cyanocobalamin Fatigue Randomized Trial | In this randomized, double-blind, placebo-controlled trial, 98 adults with IBD in remission were randomized (1:1) to receive daily supplementation with vitamins B 1 , B 6 , B 12 , and magnesium or a matching placebo for 4 weeks. | 4 | Ramezani E (2026) | Effects of B vitamins and magnesium on fatigue, disease activity and quality of life in inflammatory bowel disease. |
Source documents