topicCreatine Muscle Soreness Randomized Trial
claimClinically, EIMD is commonly reflected by delayed-onset muscle soreness (DOMS), elevated circulating creatine kinase (CK), and reduced neuromuscular performance [].
evidence level1
citationHou Chunlin (2026)
sourceAcute and Delayed Effects of Post-Exercise Recovery Strategies on Explosive Performance and Markers of Muscle Damage: A Systematic Review and Network Meta-Analysis
topicCreatine Muscle Soreness Randomized Trial
claimMassage and cryotherapy have been associated with reductions in DOMS and fatigue [], and massage has also shown favourable effects on short-term recovery of performance [].
evidence level1
citationHou Chunlin (2026)
sourceAcute and Delayed Effects of Post-Exercise Recovery Strategies on Explosive Performance and Markers of Muscle Damage: A Systematic Review and Network Meta-Analysis
topicCreatine Muscle Soreness Randomized Trial
claimAs a result, interventions that are beneficial immediately after exercise may not retain their effects during delayed recovery.
evidence level1
citationHou Chunlin (2026)
sourceAcute and Delayed Effects of Post-Exercise Recovery Strategies on Explosive Performance and Markers of Muscle Damage: A Systematic Review and Network Meta-Analysis
topicCreatine Muscle Soreness Randomized Trial
claim1 2 1 3 High-intensity training and competitive sport can induce exercise-induced muscle damage (EIMD), characterised by mechanical disruption of sarcomeres, impaired excitation-contraction coupling, and a subsequent inflammatory response [,].
evidence level1
citationHou Chunlin (2026)
sourceAcute and Delayed Effects of Post-Exercise Recovery Strategies on Explosive Performance and Markers of Muscle Damage: A Systematic Review and Network Meta-Analysis
topicCreatine Muscle Soreness Randomized Trial
claimBackground/Objectives : Although creatine (Cr) supplementation is well established for enhancing strength exercise adaptations, limited evidence exists regarding whether the timing of a single Cr dose relative to exercise acutely influences performance and related physiological and perceptual responses.
evidence level2
citationBen Maaoui K (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial.
topicCreatine Muscle Soreness Randomized Trial
claimConclusions : Pre-exercise creatine ingestion (without loading phase) was associated with greater acute strength performance compared with other timing conditions.
evidence level2
citationBen Maaoui K (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial.
topicCreatine Muscle Soreness Randomized Trial
claimThis study examined whether the timing of a single dose of Cr ingestion relative to a strength exercise session influences acute strength and power performance, cognitive function, perceptual responses, and selected blood biomarkers in physically active men.
evidence level2
citationBen Maaoui K (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial.