topicCreatine Mental Fatigue Randomized Trial
claimConclusions Creatine supplementation at 6 g/day was associated with improvements in fatigue and peripheral muscle strength in patients with PCC, with a favorable safety profile.
evidence level2
citationDos Santos MSC (2026)
sourceCreatine supplementation on fatigue related to post-COVID-19 condition-fatigue study: a randomized controlled trial.
topicCreatine Mental Fatigue Randomized Trial
claimBackground Post-COVID-19 condition (PCC) is characterized by fatigue, dyspnea, and muscle pain, with treatment including physical exercise and nutritional support.
evidence level2
citationDos Santos MSC (2026)
sourceCreatine supplementation on fatigue related to post-COVID-19 condition-fatigue study: a randomized controlled trial.
topicCreatine Mental Fatigue Randomized Trial
claimCreatine supplementation under these conditions may increase the total body creatine pool, thereby increasing muscular phosphocreatine availability and improving the energy substrate supply to sustain activity and reduce fatigue.
evidence level2
citationDos Santos MSC (2026)
sourceCreatine supplementation on fatigue related to post-COVID-19 condition-fatigue study: a randomized controlled trial.
topicCreatine Mental Fatigue Randomized Trial
claimConcurrently, the lifestyle associated with esports, characterized by physical inactivity, extended screen time, disrupted sleep cycles, and high psychological stress, poses risks to both short and long-term health [,].
evidence level4
citationGeorgiou Loizos (2026)
sourcePersonalized Nutrition, Lifestyle, and Supplementation Strategies to Support Cognitive Performance and Well-Being in Esports Athletes: A Narrative Review
topicCreatine Mental Fatigue Randomized Trial
claim7 7 8 9 10 11 7 9 10 11 12 Emerging evidence suggests that nutrition, dietary supplementation, and lifestyle habits play a crucial role in shaping both cognitive and physical performance in esports athletes [].
evidence level4
citationGeorgiou Loizos (2026)
sourcePersonalized Nutrition, Lifestyle, and Supplementation Strategies to Support Cognitive Performance and Well-Being in Esports Athletes: A Narrative Review
topicCreatine Mental Fatigue Randomized Trial
claimBalanced dietary patterns, adequate hydration, and sufficient sleep duration and quality are consistently linked to improved mental clarity, reaction times, and stress management [,].
evidence level4
citationGeorgiou Loizos (2026)
sourcePersonalized Nutrition, Lifestyle, and Supplementation Strategies to Support Cognitive Performance and Well-Being in Esports Athletes: A Narrative Review
topicCreatine Mental Fatigue Randomized Trial
claim1 2 3 4 Esports, or competitive video gaming, have evolved from a leisure activity into a structured and professionalized part of the global sports and entertainment industry.
evidence level4
citationGeorgiou Loizos (2026)
sourcePersonalized Nutrition, Lifestyle, and Supplementation Strategies to Support Cognitive Performance and Well-Being in Esports Athletes: A Narrative Review