topicCreatine Cognitive Performance Randomized Trial
claimThe importance of the timing of Cr administration is based on the assumption that exercise-induced physiological changes, such as increased hyperemia and altered transport dynamics, may optimize tissue absorption and storage [].
evidence level2
citationBen Maaoui Khouloud (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial
topicCreatine Cognitive Performance Randomized Trial
claimYet, evidence supporting specific timing strategies is restricted to a few chronic studies with conflicting findings [,,].
evidence level2
citationBen Maaoui Khouloud (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial
topicCreatine Cognitive Performance Randomized Trial
claim[] found distinct differences between pre- and post-exercise ingestion regarding strength and hypertrophy over a 32-week intervention in older adults.
evidence level2
citationBen Maaoui Khouloud (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial
topicCreatine Cognitive Performance Randomized Trial
claim1 2 3 3 4 5 6 7 Creatine (Cr) (α-methyl guanidino-acetic acid) is primarily synthesized endogenously in the kidneys and liver [,].
evidence level2
citationBen Maaoui Khouloud (2026)
sourceAcute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial
topicCreatine Cognitive Performance Randomized Trial
claimCreatine is naturally found in red meat and seafood, with trace amounts found in some plants [-].
evidence level3
citationMuacevic Alexander (2026)
sourceCreatine: Clinical Implications for Orthopedic Surgeons
topicCreatine Cognitive Performance Randomized Trial
claimAbout 95% of creatine is found within skeletal muscle, with the remaining 5% in the brain, testes, and heart.
evidence level3
citationMuacevic Alexander (2026)
sourceCreatine: Clinical Implications for Orthopedic Surgeons
topicCreatine Cognitive Performance Randomized Trial
claimThe 2013 National Collegiate Athletic Association (NCAA) National Study of Substance Use Habits of College Student Athletes found that 13.2% used creatine in the last year [].
evidence level3
citationMuacevic Alexander (2026)
sourceCreatine: Clinical Implications for Orthopedic Surgeons
topicCreatine Cognitive Performance Randomized Trial
claim1 1 3 4 5 6 3 6 1 4 7 3 Owing to the popularity of nutritional supplements, the orthopedic surgeon will surely encounter patients taking creatine.
evidence level3
citationMuacevic Alexander (2026)
sourceCreatine: Clinical Implications for Orthopedic Surgeons