Coenzyme Q10 Supplementation Exercise Performance Randomized Trial Evidence Table

Structured evidence table for Coenzyme Q10 Supplementation Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialNT-proBNP increased post-Ex1 (19.66%, p = 0.001), post-Ex2 (12.09%, p = 0.001) but decreased in 24 h-Ex1 (- 20.28%, p = 0.001), 24 h-Ex2 (-20.83%, p = 0.001) compared to post-Ex1&Ex2, respectively.2Rahimi MR (2025)Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialTime to fatigue (TTF) improved post-supplementation (- 0.5%, p = 0.002), whereas the placebo showed no change (- 0.08%, p = 0.793).2Rahimi MR (2025)Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialConclusions CoQ10 supplementation significantly reduced post-exercise cardiac stress markers (GDF-15, NT-proBNP, hs-TnT) and improved TTF in athletes.2Rahimi MR (2025)Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialBackground Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes.2Rahimi MR (2025)Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialThe reduced form of CoQ 10 , ubiquinol (UQH 2 ), has greater bioavailability than ubiquinone, but the effects of UQH 2 supplementation on mitochondrial respiratory function and exercise capacity are unclear.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialCompared to pre-supplementation and PLA, UQH 2 supplementation increased plasma [CoQ 10 ] (P 2 : 0.073 ± 0.039 vs.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialSix-weeks UQH 2 supplementation increased plasma [CoQ 10 ] and oxidative phosphorylation coupling efficiency, but did not alter mitochondrial leak proteins, T Lim or V̇O 2 kinetics during severe-intensity exercise in healthy, active males.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Coenzyme Q10 Supplementation Exercise Performance Randomized TrialCoenzyme Q10 (CoQ 10 ) is an integral component of the mitochondrial electron transfer system.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimNT-proBNP increased post-Ex1 (19.66%, p = 0.001), post-Ex2 (12.09%, p = 0.001) but decreased in 24 h-Ex1 (- 20.28%, p = 0.001), 24 h-Ex2 (-20.83%, p = 0.001) compared to post-Ex1&Ex2, respectively.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimTime to fatigue (TTF) improved post-supplementation (- 0.5%, p = 0.002), whereas the placebo showed no change (- 0.08%, p = 0.793).
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimConclusions CoQ10 supplementation significantly reduced post-exercise cardiac stress markers (GDF-15, NT-proBNP, hs-TnT) and improved TTF in athletes.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimBackground Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimThe reduced form of CoQ 10 , ubiquinol (UQH 2 ), has greater bioavailability than ubiquinone, but the effects of UQH 2 supplementation on mitochondrial respiratory function and exercise capacity are unclear.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimCompared to pre-supplementation and PLA, UQH 2 supplementation increased plasma [CoQ 10 ] (P 2 : 0.073 ± 0.039 vs.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimSix-weeks UQH 2 supplementation increased plasma [CoQ 10 ] and oxidative phosphorylation coupling efficiency, but did not alter mitochondrial leak proteins, T Lim or V̇O 2 kinetics during severe-intensity exercise in healthy, active males.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimCoenzyme Q10 (CoQ 10 ) is an integral component of the mitochondrial electron transfer system.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.

Source documents

  1. Short-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
  2. Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.