topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimNT-proBNP increased post-Ex1 (19.66%, p = 0.001), post-Ex2 (12.09%, p = 0.001) but decreased in 24 h-Ex1 (- 20.28%, p = 0.001), 24 h-Ex2 (-20.83%, p = 0.001) compared to post-Ex1&Ex2, respectively.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimTime to fatigue (TTF) improved post-supplementation (- 0.5%, p = 0.002), whereas the placebo showed no change (- 0.08%, p = 0.793).
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimConclusions CoQ10 supplementation significantly reduced post-exercise cardiac stress markers (GDF-15, NT-proBNP, hs-TnT) and improved TTF in athletes.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimBackground Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes.
evidence level2
citationRahimi MR (2025)
sourceShort-term CoQ10 supplementation reduces markers of cardiac stress in soccer players following heavy exercise: A randomized double-blind placebo-controlled trial.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimThe reduced form of CoQ 10 , ubiquinol (UQH 2 ), has greater bioavailability than ubiquinone, but the effects of UQH 2 supplementation on mitochondrial respiratory function and exercise capacity are unclear.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimCompared to pre-supplementation and PLA, UQH 2 supplementation increased plasma [CoQ 10 ] (P 2 : 0.073 ± 0.039 vs.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimSix-weeks UQH 2 supplementation increased plasma [CoQ 10 ] and oxidative phosphorylation coupling efficiency, but did not alter mitochondrial leak proteins, T Lim or V̇O 2 kinetics during severe-intensity exercise in healthy, active males.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicCoenzyme Q10 Supplementation Exercise Performance Randomized Trial
claimCoenzyme Q10 (CoQ 10 ) is an integral component of the mitochondrial electron transfer system.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.