topicCoconut Oil Cognition Randomized Trial
claimIn addition to the reduced quality of life and wellbeing for the patient, ADRD also imposes a cost on society through the significant financial burden of patient care ().
evidence level1
citationBonnechère Bruno (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis
topicCoconut Oil Cognition Randomized Trial
claim() found that ketones entering the brain via select, widely expressed mono-carboxylate transporters () can account for up to 60% of brain metabolic needs during prolonged starvation.
evidence level1
citationBonnechère Bruno (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis
topicCoconut Oil Cognition Randomized Trial
claim16 17 20 21 17 22 21 17 Ketones are produced endogenously, as a result of increased peripheral lipolysis and hepatic conversion of free fatty acids to ketone bodies ().
evidence level1
citationBonnechère Bruno (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis
topicCoconut Oil Cognition Randomized Trial
claim1 2 3 Cognitive function is fundamental to independence, quality of life, and healthy aging, and is influenced by both physiological and pathological processes across the lifespan.
evidence level1
citationBonnechère Bruno (2026)
sourceThe effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis
topicCoconut Oil Cognition Randomized Trial
claimand) Do high-fat meals result in a greater increase in PYY compared with lower-fat meals (fat amount effect)?
evidence level2
citationDiekmann Christina (2026)
sourceFat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial
topicCoconut Oil Cognition Randomized Trial
claimFurthermore, ≥2 of the following characteristics of metabolic syndrome had to apply []:) dyslipidemia (serum triglycerides ≥1.7 mmol/L and/or serum HDL cholesterol <1.03 mmol/L for men and <1.29 mmol/L for women),) increased resting blood pressure (systolic BP ≥130 mmHg and/or diastolic BP ≥85 mmHg), and) increased plasma glucose (≥5.6 mmol/L).
evidence level2
citationDiekmann Christina (2026)
sourceFat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial
topicCoconut Oil Cognition Randomized Trial
claimAll participants were overweight (48.3%) or obese (51.7%), had a visceral fat distribution, an increased resting BP, and an increased plasma glucose concentration [].
evidence level2
citationDiekmann Christina (2026)
sourceFat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial
topicCoconut Oil Cognition Randomized Trial
claim1 2 3 4 5 6 [6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] 11 19 15 19 7 Eating behavior is regulated by a complex interplay of homeostatic and nonhomeostatic mechanisms [].
evidence level2
citationDiekmann Christina (2026)
sourceFat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial