topicCocoa Flavanols Exercise Performance Randomized Trial
claimGrowing evidence indicates that these bioactive compounds can modulate intracellular signaling pathways and induce adaptive cellular responses, including mechanisms consistent with mitohormesis, thereby enhancing cellular stress resistance and metabolic flexibility [].
evidence level3
citationFazekas-Pongor Vince (2026)
sourcePhysiological and Recovery Responses to Dietary Polyphenols in the Context of Exercise: Relevance for Muscle Aging and Sarcopenia
topicCocoa Flavanols Exercise Performance Randomized Trial
claimThis overlap raises the possibility that factors influencing recovery responses may have relevance for aging muscle, although direct clinical evidence supporting this translational link is still limited.
evidence level3
citationFazekas-Pongor Vince (2026)
sourcePhysiological and Recovery Responses to Dietary Polyphenols in the Context of Exercise: Relevance for Muscle Aging and Sarcopenia
topicCocoa Flavanols Exercise Performance Randomized Trial
claimThe present narrative review synthesizes and critically interprets evidence on the physiological and recovery-related effects of dietary polyphenols in the context of exercise and skeletal muscle function, examining their potential translational relevance for muscle aging and sarcopenia.
evidence level3
citationFazekas-Pongor Vince (2026)
sourcePhysiological and Recovery Responses to Dietary Polyphenols in the Context of Exercise: Relevance for Muscle Aging and Sarcopenia
topicCocoa Flavanols Exercise Performance Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 18 19 20 21 22 Skeletal muscle adaptation to exercise and the subsequent recovery process are key determinants of physical performance, functional capacity, and long-term muscle health [].
evidence level3
citationFazekas-Pongor Vince (2026)
sourcePhysiological and Recovery Responses to Dietary Polyphenols in the Context of Exercise: Relevance for Muscle Aging and Sarcopenia
topicCocoa Flavanols Exercise Performance Randomized Trial
claimMetS is a multifactorial condition, with its primary indicators including obesity, hypertension, dyslipidemia, insulin resistance, and hyperglycemia; i.e., a patient who possesses at least 3 of the following parameters is designated with MetS: glucose intolerance, increased levels of triglycerides, augmented waist circumference, low levels of high-density lipoprotein cholesterol (HDL-c), and hypertension [,,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Exercise Performance Randomized Trial
claimIt is possible to develop a close relationship with MetS, metabolic dysfunction-associated steatotic liver disease (MASLD), and CVD [,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Exercise Performance Randomized Trial
claimMASLD is strongly associated with various conditions, including MetS, and is characterized by the persistence of a chronic inflammatory state detrimental to the organism [,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Exercise Performance Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 Metabolic disorders are increasing sharply due to severe modifications in lifestyle [,,,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors